Training Program in Pediatric Infectious Diseases

描述（由申请人提供）：本申请要求支持五名博士后学员（四名医学博士）。一个博士）每年学习儿科传染病和国际卫生研究的原则和实践。 我们的目标是培养下一代学术传染病研究人员，他们特别关注与美国和国外儿童相关的传染病问题。 这是一个新项目，但我们已经建立了培训年轻儿科传染病医生科学家的记录，其中许多人已经在学术医疗中心担任NIH资助的研究型教师职位。我们现在建议建立一个NIH资助的培训计划，将仔细监督的研究置于培训经验的核心。 已组织的培训教师包括22名研究人员，其中20名获得NIH的校外支持，分为三个研究重点领域：宿主防御，发病机制和国际卫生/寄生虫学。医学博士的临床职责研究员将主要是在奖学金的第一年，这将是由部门的支持，离开第二和第三年严格屏蔽的研究工作。 第四年的研究将提供给那些需要更多实验室经验的学员，并将由本补助金以外的其他来源提供支持。所有受训者必须完成临床研究入门课程，包括生物统计学，基础免疫学和研究道德行为课程。此外，学员将参加每周的研究研讨会和期刊俱乐部。对从事国际卫生研究感兴趣的研究员也必须完成国际卫生课程。学员将选择一名研究导师，并由执行委员会监督，执行委员会将每半年检查一次每位学员的进展情况，并为导师和学员提供书面反馈。学员将准备摘要，演示文稿和论文，大多数将在培训的最后一年写K奖赠款。该方案将由一个国家咨询委员会审查，以确定方案发展的长处和短处。这个以研究为重点的计划与内部和外部监督将提供儿科传染病学员所需的技能，以执行假设驱动的基础和临床研究，并通过产生校外支持在学术环境中生存。

DESCRIPTION (provided by applicant): This application requests support for five post-doctoral trainees (four M.D. and one Ph.D.) per year to learn the principles and practices of research in Pediatric Infectious Diseases and International Health. It is our goal to train the next generation of academic infectious diseases researchers who have particular focus on infectious diseases problemsthat are relevant to children in the United States and abroad. This is a new program, but we have already established a track record of training young Pediatric Infectious Diseases physician scientists many of whom have assumed NIH- funded research-oriented faculty positions at Academic Medical Centers. We now propose to establish a NIH-funded training program that places carefully supervised research at the heart of the training experience. The training faculty that has been organized includes 22 investigators, 20 with NIH extramural support grouped into three areas of research focus: Host Defense, Pathogenesis, and International Health/ Parasitology. Clinical responsibilities for M.D. fellows will primarily be in the first year of fellowship, which will be supported by the Department, leaving the second and third years strictly shielded for research endeavors. A fourth year of research will be available for those trainees requiring more laboratory experience, and will be supported by other sources than this grant. All trainees must complete a course in Introduction to Clinical Research including Biostatistics, Fundamental Immunology, and a course in the Ethical Conduct of Research. In addition, trainees will attend weekly Research Seminar and Journal Club. Those fellows interested in pursuing research in International Health will also be required to complete the International Health Course. Trainees will choose a research mentor and have oversight by an Executive Committee, which will semi-annually examine the progress of each trainee and generate written feedback for both mentor and trainee. Trainees will prepare abstracts, presentations and papers, and most will write K award grants in their final year of training. The program will be reviewed by a National Advisory Committee to determine both strengths and weaknesses as the program develops. This research-focused program with internal and external oversight will provide Pediatric Infectious Diseases trainees with the skills required to perform hypothesis driven basic and clinical research and survive in the academic environment via generation of extramural support.