Biology of Infectious Diseases & Inflammation

描述（由申请人提供）：本提案是一项竞争性更新培训补助金的请求，用于资助我们传染病和炎症项目（IDIP）的四名博士前和两名博士后学员。IDIP由19名受资助的研究人员组成，他们都被列为这项资助的学员，我们的学员，初级教员（未被列为培训师）以及支持传染病和炎症研究的行政和技术人员。教师的专业领域可以大致分为四个兴趣领域：再发细菌感染的发病机制(3)，生物防御和新发病毒感染(5)，癌症作为一种传染性病毒疾病(3)和基本炎症和免疫机制(8)。培训教员包括17名在新墨西哥大学（UNM）医学院（SOM）的四个系任职的教员，包括内科（4名）、分子遗传学和微生物学（6名）、病理学（6名）和细胞生物学和生理学（1名），或在洛夫莱斯呼吸研究所（2名）任职。培训计划的目标是：1)通过提供研究报告、期刊俱乐部、研讨会和课程开发的场所，丰富传染病和炎症的跨学科研究；2)提供丰富的合作教育研究环境，为博士后和博士后学员提供向各种各样的科学家、他们的技术人员和其他学员学习的机会；3)提供专业指导，包括科学伦理方面的指导和体验式培训、教学和各种科学职业的机会。该计划是从已经进入新墨管理学院跨学科生物医学科学研究生项目（BSGP）的博士生中招募奖学金实习生，这些博士生选择在IDIP教员的实验室工作。博士后候选人将从DIP学院实验室招募的合格博士后学员中选拔。被选中的受训者将由其特定的idp培训师指导（博士生预科生有两到三年的培训资助，博士后受训者有两年的培训资助），他们的进展将由idp指导委员会定期审查。除了BSGP规定的博士预科生必须学习的课程外，所有人都需要学习ipp特定的课程。该项目得到了新墨西哥州管理学院和LRRI的大力支持，SOM或LRRI共同资助所有第一年的学生，BSGP和部门联合支持该项目的管理，包括所有招聘费用。我们的项目包含了特殊的和不寻常的优势，学员将接触到非常广泛的教学培训和实验室经验，使他们接触到优秀的跨学科核心设施、强大的生物技术（公司）合作、国际项目（如ICIDR/Fogarty项目）、高致病性潜在生物武器、卓越的结构生物学和成像能力，以及发达的生物工程研究伙伴关系。

DESCRIPTION (provided by applicant): This proposal is a request for competitive renewal of a training grant to fund four predoctoral and two postdoctoral trainees in our Infectious Disease and Inflammation Program (IDIP). IDIP is comprised of a group of 19 funded investigators, all listed as trainees on this grant, our trainees, junior faculty (not listed a trainers) and administrative and technical staff who support research in infectious disease and inflammation. The areas of expertise of the faculty can be broadly grouped into four areas of interest: Pathogenesis of Reemerging Bacterial Infections (3), Biodefense and Emerging Viral Infections (5), Cancer as a Communicable Viral Disease (3) and Basic Inflammatory and Immunologic Mechanisms (8). The training faculty include 17 who have appointments in four University of New Mexico (UNM) School of Medicine (SOM) departments that include Internal Medicine (4), Molecular Genetics and Microbiology (6), Pathology (6), and Cell biology and Physiology (1)] or at Lovelace Respiratory Research Institute (2). The goals of the training program are to: 1) enrich interdisciplinary research in infectious diseases and inflammation by providing venues for research presentations, journal clubs, seminars and course development; 2) provide a rich, cooperative educational research environment with opportunities for both pre- and postdoctoral trainees to learn from a wide variety of scientists, their technicians and other trainees; and 3) to provide professional guidance, including instruction and experiential training in scientific ethics, teaching, and opportunities in diverse scientific careers. The plan is to recruit fellowship trainees from among those predoctoral students who have already matriculated in UNM SOM's interdisciplinary Biomedical Sciences Graduate Program (BSGP) who choose to work in the laboratories of IDIP faculty member. The postdoctoral candidates will be selected from qualified postdoctoral trainees recruited to DIP faculty laboratories. The selected trainees would be mentored (with two to three years of training grant support for predoctoral students and two years for postdoctoral trainees) by their specific IDIP trainer, and their progress will be regularly reviewed by the IDIP steering committee. All would be expected to take IDIP-specific courses, in addition to those courses that the predoctoraI trainees are required to take as specified by the BSGP. The program is strongly supported by both UNM SOM and the LRRI as evidenced by the SOM or LRRI jointly funding fully all first year students and by joint BSGP and departmental support for administration of the program, including all recruiting costs. Our program includes specific and unusual strengths in that trainees are exposed to didactic training and laboratory experiences that are very broad and that expose them to excellent interdisciplinary core facilities, strong biotechnotogy (corporate) collaborations, international programs (such as an ICIDR/Fogarty program), work with highly pathogenic potential bioweapons, superb structural biology and imaging capabilities, and well-developed bioengineering research partnerships.