Radiation Biology Training Grant

描述（由申请人提供）：这是一个竞争性的更新， 一项旨在培训放射生物学家的计划的培训补助金提案 他们将了解分子，细胞和组织的影响， 辐射需要6名博士前和6名博士后培训生。培训 将在辐射生物学和相关实验室提供， 宾夕法尼亚大学肿瘤学研究部 药该计划将涉及正式的课程工作，一系列讲座和一个 期刊俱乐部专为我们的培训需求，研究研讨会和 会议和实验室研究项目由常设 investigators.研究项目将集中在各个方面的 参与实验室目前资助的研究领域; 研究项目，学员将利用现代技术开发的 生物学在辐射中进行机械导向的研究 生物学/肿瘤学。12名培训主任和 参与的主管人员广泛从事癌症研究，包括 致癌和致突变的分子机制，分子和细胞 辐射生物学，辐射化学和生物化学，DNA修复过程， 癌症预防和放射肿瘤学。预计毕业生 培训计划将继续与他们的研究和学术生涯， 放射生物学和肿瘤学。

DESCRIPTION (provided by applicant): This is a competitive renewal of a training grant proposal for a program designed to train radiation biologists who will have knowledge of the molecular, cellular and tissue effects of radiation. 6 predoctoral and 6 postdoctoral trainees are requested. Training will be offered in the radiation biology and associated laboratories of the Division of Oncology Research at the University of Pennsylvania School of Medicine. The program will involve formal course work, a lecture series and a journal club designed for our training needs, research seminars and conferences and laboratory research projects to be supervised by established investigators. The research projects will focus on various aspects of the currently funded research areas in the participating laboratories; for research projects, trainees will utilize techniques developed in modern biology to perform mechanistically-oriented studies in radiation biology/oncology. The research areas in which the 12 training directors and supervisors are involved are broadly based in cancer research, including molecular mechanisms of carcinogenesis and mutagenesis, molecular and cellular radiation biology, radiation chemistry and biochemistry, DNA repair processes, cancer prevention and radiation oncology. It is expected that graduates of the training program will continue with their research and academic careers in radiation biology and oncology.