CORE--X RAY CRYSTALLOGRAPHY

描述：（申请人的描述）X射线晶体学已经有了一个 作为癌症中心的重要研究元素，历史悠久。它 提供最先进的X射线衍射仪器（四台理学公司 旋转阳极X射线发生器，三个西门子多线区域探测器，一个 MacScience衍射图像处理器、理学R轴IIc和理学 R轴IV）和计算机/图形（SGI Power Onyx，两个SGI Maximum Impact 图形工作站、新的Origin 2000计算服务器和DEC Alpha 2200 服务器）。该设施支持七个癌症中心的工作 与癌症中心教师有多次合作的晶体学家 在其他节目中。该设施为51提供计算机/图形支持 今年以来，在8个项目中。该设施位于6，500 NASF的 癌症中心空间以及1，200 NASF“虚拟”剧院 Onyx联动大屏幕立体立体投影。该设施是 癌症中心结构生物学计划的一个组成部分， 强调结构：功能关系，分子建模和药物 设计

Description: (Applicant's Description) The X-ray Crystallography has had a long history as an important research element of the Cancer Center. It provides state-of-the-art x-ray diffraction instrumentation (four Rigaku rotating anode x-ray generators, three Siemans Multiwire area detectors, one MacScience diffraction image processor, a Rigaku R-axis IIc, and a Rigaku R-axis IV) and computer/graphics (SGI Power Onyx, two SGI Maximum Impact graphic stations, a new Origin 2000 compute server and a DEC Alpha 2200 server). The facility supports the work of seven Cancer Center crystallographers who have multiple collaborations with Cancer Center faculty in other programs. The facility provided computer/graphics support to 51 faculty in 8 programs this past year. The facility is housed in 6,500 NASF of Cancer Center space as well as a 1,200 NASF "virtual" theater for Power Onyx-linked large screen three-dimensional stereo projection. The facility is an integral component of the Cancer Center's Structural Biology Program with an emphasis on structure: function relationships, molecular modeling and drug design.