PILOT--DEVELOPMENTAL RESEARCH PROGRAM

前列腺癌孢子发育研究计划的总体目标是为前列腺癌有希望的试点翻译提供初始资金。该计划将强调对转化性研究项目的支持，这些项目可以产生临床可检验的假设，有助于我们降低前列腺癌的发病率和死亡率，或提高前列腺癌患者的生活质量。孢子行政核心将向包括孢子职业发展计划参与者在内的所有机构调查人员征求不超过5页的创新翻译研究提案。行政核心将帮助提交建议的调查人员制定翻译的具体目标和研究计划，因为这些调查人员中的许多人在这一领域没有专业知识。因此，这一过程将是一项重大的教育活动，并将进一步刺激制定创新的翻译具体目标和研究计划，因为这些调查人员中的许多人将不具备这一领域的专业知识。因此，这一过程将是一项重要的教育活动，并将进一步刺激创新的翻译研究概念的发展。执行委员会将使用客观标准对相互竞争的提案进行筛选。然后，选定提案的调查人员将仿照NIH R01准备一份10页的提案。然后，将利用客观标准将这些建议转交给外部科学咨询委员会的成员。然后，选定提案的调查人员将仿照NIH R01准备一份10页的提案。然后，选定提案的调查人员将仿照NIH R01准备一份10页的提案。然后，这些建议将转发给外部科学咨询委员会成员，以确定优先次序。这些项目的资金将为1年，并将可续期一年。作为我们继续努力扩大MDACC研究的一部分。已在全机构范围内宣布和征集试点项目。在提交的18个项目中，有7个被认为是纯粹的基础项目，虽然有价值，但与孢子的翻译重点不一致。其余11名调查人员均作了陈述。此外，每个研究人员都提交了一份结构化摘要，概述了提案、其潜在影响以及支持其可行性的初步数据。在11个项目中，有6个项目被评为值得试点资助。这里提出的六项有价值的建议说明了这一进程在选择候选项目方面的成功。

The overall aim of the SPORE Developmental Research Program in Prostate Cancer is to provide initial funding for promising pilot translational in prostate cancer. The program will emphasize the support of translational research projects that can generate clinically testable hypotheses that will help us reduce the incidence and mortality of prostate cancer or improve the quality of life of prostate cancer patients. Proposals of no more than 5 pages for innovative translational research will be solicited by the SPORE Administrative Core from all institutional investigators, including participants in the SPORE Career Development Program. The Administrative Core will help the investigators submitted proposals formulate translational specific aims and research plans, as many of these investigators will not have expertise in this area.. The process will therefore be a major educational activity and will further stimulate the development of innovative translational specific aims and research plans, as many of these investigators will not have expertise in this area. The process will therefore be a major educational activity and will further stimulate the development of innovative translational research concepts. Competing proposals will be screened by the Executive Committee by using objective criteria. Investigators of selected proposals will then prepare a 10-page proposal modeled after an NIH R01. The proposals will be then forwarded to members of the External Scientific Advisory Committee by using objective criteria. Investigators of selected proposals will then prepare a 10-page proposal modeled after a NIH R01. Investigators of selected proposals will then prepare a 10- page proposal modeled after an NIH R01. The proposals will be then forwarded to members of the External Scientific Advisory Committee for prioritization. The projects will be funded for 1 year and will be renewable for an additional year. As part of our continuing efforts to expand research at MDACC. An institution wide announcement and solicitation for pilot projects was made. Of 18 projects submitted, seven were considered to be purely basic and, although meritorious, not consistent with the translational focus of the SPORE. Presentations were made by each of the remaining 11 investigators. In addition, each investigator submitted a structured abstract outlining the proposals, its potential impac5t, and the preliminary data to support its feasibility. Of the 11 projects, six were judged to be worthy of pilot funding. The six worthy proposals presented here illustrate the success of the process in selecting candidate projects.