Using novel phenomics technology for environmental sensitivity prediction in marine invertebrates

这位博士将应用一项新的尖端技术--胚胎表现学，来开发预测海洋无脊椎动物环境敏感性的新工具。对生物体将如何应对全球变化的准确预测是一项重大的科学挑战，但对于制定政策决策和缓解战略至关重要。表型组学是一种新的技术支持的方法，它使用高通量获取可观察表型(即形态、生理和行为)的高维数据，以更稳健地测量生物反应，并提供对支撑敏感性的机制的更全面的理解。胚胎表现学使用生物成像和先进的图像分析来测量具有不同生活史策略的水生物种早期发育阶段的敏感性，并将被用于产生可用作预测工具的新的亚致死现象终点。

This PhD will apply a new, cutting-edge technology, EmbryoPhenomics, to develop novel tools for predicting environmental sensitivity in marine invertebrates. The accurate prediction of how organisms will respond to global change represents a significant scientific challenge but is essential for developing policy decisions and mitigation strategies. Phenomics is a new, technology-enabled approach that uses the high-throughput acquisition of high-dimensional data of the observable phenotype (i.e. morphology, physiology and behaviour) to measure biological responses more robustly and provide a more holistic understanding of the mechanisms underpinning sensitivity. EmbryoPhenomics uses bio-imaging and advanced image analysis to measure the sensitivity of early developmental stages in aquatic species with different life history strategies and will be used to produce novel, sub-lethal phenomic end points that can be used as predictive tools.