COLUMBIA/ROCKEFELLER CENTER FOR AIDS RESEARCH
COLUMBIA/ROCKEFELLER CENTER FOR AIDS RESEARCH
批准号:
6534100
负责人:
Scott M Hammer
金额:
$135.8万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-09-01 至 2005-07-31
关键词:
中文摘要
洛克菲勒大学(RU)校长托尔斯滕·威茨博士和
哥伦比亚大学(CU)医学院院长赫伯特帕德斯(Herbert Pardes),
共同提议建立哥伦比亚-洛克菲勒中心,
艾滋病研究(CR-CFAR),一个连接艾滋病的行政结构
来自我们位于纽约市的两所大学的调查人员。
CR-CFAR将由大卫博士监督的一系列附例管理
何(主任,亚伦钻石艾滋病研究中心,RU)和杰里米鲁班
(CU分子病毒学部门负责人)和执行指导
委员会成员包括:Yuan Chang博士、伦纳德Chess博士、Anke Ehrhardt博士、
斯蒂芬·戈夫、韦恩·亨德里克森、马丁·马科维茨、普雷斯顿、马克思、约翰
摩尔和拉尔夫·斯坦曼。CR-CFAR成员将包括
来自亚伦·戴蒙德艾滋病研究中心的70多名研究人员
(RU)纽约艾滋病临床和行为研究中心
国家精神病研究所(CU),一般临床研究中心
(GCRC)在RU医院,哥伦比亚大学儿科和成人
ACTU,在哥伦比亚长老会医疗中心的临床部门看到
中心和哈莱姆医院医疗中心(CU),
CU和RU的基础科学,以及实验室
医学和外科在灵长类动物(RU)。两个目标统一了所有CR-CFAR
参与者第一个目标是更多地了解
艾滋病毒的复制、传播和发病机制,研究范围从
病毒蛋白质结构的原子解析与心理社会动力学
市中心社区第二个目标是整合这个
将信息转化为开发抗病毒疗法和疫苗的项目,
以及社区外展和信息,
治疗和疫苗,以及社区外展和行为
干预策略。通过支持七个可修改的核心设施,
(管理,开发,病毒学,免疫学,临床资源,
结构生物学和灵长类生物学),CR-CFAR将促进三个
主要目标:1)加强优秀的研究计划,
已经到位,通过提供,或简单地使更容易获得,
共享研究设施; 2)帮助招募初级教师到我们的
计划和我们的机构,并鼓励建立
从我们的教师队伍中挑选调查人员,
艾滋病相关主题的方案; 3)促进对话,
与CR-CFAR成员进行富有成效的合作。
英文摘要
Dr. Torsten Wiesel, President of the Rockefeller University (RU), and Dr.
Herbert Pardes, Dean of the Medical Faculty of Columbia University (CU),
jointly propose the establishment of the Columbia-Rockefeller Center for
AIDS Research (CR-CFAR), an administrative structure bridging AIDS
investigators from our two Universities located in the City of New York.
The CR-CFAR will be governed by a series of by-laws overseen by Drs. David
Ho (Director, Aaron Diamond AIDS Research Center, RU) and Jeremy Luban
(Chief, Division of Molecular Virology, CU), and by an Executive Steering
Committee consisting of Drs. Yuan Chang, Leonard Chess, Anke Ehrhardt,
Stephen Goff, Wayne Hendrickson, Martin Markowitz, Preston Marx, John
Moore, and Ralph Steinman. The CR-CFAR membership will be comprised of
over 70 investigators drawn from the Aaron Diamond AIDS Research Center
(RU), the HIV Center for Clinical and Behavioral Studies at the New York
State Psychiatric Institute (CU), the General Clinical Research Center
(GCRC) at the RU Hospital, the Columbia University Pediatric and Adult
ACTUs, seen clinical departments at the Columbia-Presbyterian Medical
Center and at the Harlem Hospital Medical Center (CU), ten departments of
basic science at CU and RU, as well as the Laboratory for Experimental
Medicine and Surgery in Primates (RU). Two goals unify all CR-CFAR
participants. The fist goal is to understand more about the mechanism of
HIV replication, transmission, and pathogenesis, with studies ranging from
atomic resolution of viral protein structure to the psycho-social dynamics
of the inner city community. The second goal is to integrate this
information into programs developing anti-viral therapeutics and vaccines,
and community outreach and information into programs developing anti-viral
therapeutics and vaccines, and community outreach and behavioral
intervention strategies. By supporting seven modifiable core facilities
(Administration, Development, Virology, Immunology, Clinical Resources,
Structural Biology, and Primate Biology), the CR-CFAR will promote three
major objectives: 1) to enhance the outstanding research programs that are
already in place by providing,, or simply rendering more accessible,
shared research facilities; 2) to help recruit junior faculty to our
programs and to our institutions, and to encourage established
investigators from within the ranks of our faculty to develop research
programs in AIDS-related topics; and 3) to promote dialogue leading to new
productive collaborations involving CR-CFAR members.
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Single-dose nevirapine and drug resistance: the more you look, the more you find.
单剂量奈韦拉平与耐药性:你看得越多,发现的就越多。
DOI:
10.1086/430745
发表时间:
2005
期刊:
The Journal of infectious diseases
影响因子:
--
作者:
[Hammer,ScottM]
通讯作者:
Hammer,ScottM
DOI:
10.1084/jem.20041196
发表时间:
2004-09-20
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
[Mehandru S, Poles MA, Tenner-Racz K, Horowitz A, Hurley A, Hogan C, Boden D, Racz P, Markowitz M]
通讯作者:
Markowitz M
DOI:
10.1097/qai.0b013e31817ecb31
发表时间:
2008-08-15
期刊:
Journal of acquired immune deficiency syndromes (1999)
影响因子:
--
作者:
[Mohri H, Markowitz M]
通讯作者:
Markowitz M
Infection with multidrug resistant, dual-tropic HIV-1 and rapid progression to AIDS: a case report.
多重耐药性、双向性 HIV-1 感染和快速进展为艾滋病:病例报告。
DOI:
10.1016/s0140-6736(05)71139-9
发表时间:
2005
期刊:
Lancet (London, England)
影响因子:
--
作者:
[Markowitz,Martin, Mohri,Hiroshi, Mehandru,Saurabh, Shet,Anita, Berry,Leslie, Kalyanaraman,Roopa, Kim,Alexandria, Chung,Chris, Jean-Pierre,Patrick, Horowitz,Amir, LaMar,Melissa, Wrin,Terri, Parkin,Neil, Poles,Michael, Petropoulos,Christos, ]
通讯作者:
A randomized open-label study of 3- versus 5-drug combination antiretroviral therapy in newly HIV-1-infected individuals.
对新近HIV-1感染的个体的3-药物组合抗逆转录病毒疗法的随机开放标签研究。
DOI:
10.1097/qai.0000000000000111
发表时间:
2014-06-01
期刊:
Journal of acquired immune deficiency syndromes (1999)
影响因子:
--
作者:
[Markowitz M, Evering TH, Garmon D, Caskey M, La Mar M, Rodriguez K, Sahi V, Palmer S, Prada N, Mohri H]
通讯作者:
Mohri H
共 7 条
Columbia Integrated Training Program in Infectious Disease Research
-
批准号:8675797
-
项目类别:
-
资助金额:$15.87万
-
财政年份:2013
-
负责人:Scott M Hammer
-
依托单位:
Columbia Integrated Training Program in Infectious Diseases Research
-
批准号:9918843
-
项目类别:
-
资助金额:$15.25万
-
财政年份:2013
-
负责人:Scott M Hammer
-
依托单位:
Columbia Integrated Training Program in Infectious Disease Research
-
批准号:8827666
-
项目类别:
-
资助金额:$16.1万
-
财政年份:2013
-
负责人:Scott M Hammer
-
依托单位:
Columbia Integrated Training Program in Infectious Disease Research
-
批准号:8551359
-
项目类别:
-
资助金额:$7.69万
-
财政年份:2013
-
负责人:Scott M Hammer
-
依托单位:
Columbia Integrated Training Program in Infectious Disease Research
-
批准号:9033056
-
项目类别:
-
资助金额:$13.47万
-
财政年份:2013
-
负责人:Scott M Hammer
-
依托单位:
Columbia Collaborative HIV/AIDS Clinical Trials Unit
-
批准号:7896935
-
项目类别:
-
资助金额:$160.15万
-
财政年份:2009
-
负责人:Scott M Hammer
-
依托单位:
Columbia Collaborative HIV/AIDS Clinical Trials Unit
-
批准号:7994799
-
项目类别:
-
资助金额:$229.6万
-
财政年份:2007
-
负责人:Scott M Hammer
-
依托单位:
Columbia Collaborative HIV/AIDS Clinical Trials Unit
-
批准号:8391240
-
项目类别:
-
资助金额:$242.57万
-
财政年份:2007
-
负责人:Scott M Hammer
-
依托单位:
Columbia Collaborative HIV/AIDS Clinical Trials Unit
-
批准号:7096377
-
项目类别:
-
资助金额:$328.61万
-
财政年份:2007
-
负责人:Scott M Hammer
-
依托单位:
Columbia Collaborative HIV/AIDS Clinical Trials Unit
-
批准号:8197559
-
项目类别:
-
资助金额:$264.46万
-
财政年份:2007
-
负责人:Scott M Hammer
-
依托单位:
Columbia Collaborative HIV/AIDS Clinical Trials Unit
-
批准号:7569402
-
项目类别:
-
资助金额:$293.1万
-
财政年份:2007
-
负责人:Scott M Hammer
-
依托单位:
Columbia Collaborative HIV/AIDS Clinical Trials Unit
-
批准号:7743077
-
项目类别:
-
资助金额:$239.82万
-
财政年份:2007
-
负责人:Scott M Hammer
-
依托单位:
Columbia Collaborative HIV/AIDS Clinical Trials Unit
-
批准号:7345377
-
项目类别:
-
资助金额:$287.83万
-
财政年份:2007
-
负责人:Scott M Hammer
-
依托单位:
COLUMBIA-ADARC-CORNELL AIDS CLINICAL TRIALS UNIT
-
批准号:6626366
-
项目类别:
-
资助金额:$153.5万
-
财政年份:2000
-
负责人:Scott M Hammer
-
依托单位:
COLUMBIA-ADARC-CORNELL AIDS CLINICAL TRIALS UNIT
-
批准号:6692982
-
项目类别:
-
资助金额:$160.47万
-
财政年份:2000
-
负责人:Scott M Hammer
-
依托单位:
COLUMBIA-ADARC AIDS CLINICAL TRIALS UNIT
-
批准号:6341741
-
项目类别:
-
资助金额:$153.79万
-
财政年份:2000
-
负责人:Scott M Hammer
-
依托单位:
COLUMBIA-ADARC AIDS CLINICAL TRIALS UNIT
-
批准号:6022181
-
项目类别:
-
资助金额:$117.65万
-
财政年份:2000
-
负责人:Scott M Hammer
-
依托单位:
COLUMBIA-ADARC-CORNELL AIDS CLINICAL TRIALS UNIT
-
批准号:7019766
-
项目类别:
-
资助金额:$158.2万
-
财政年份:2000
-
负责人:Scott M Hammer
-
依托单位:
COLUMBIA-ADARC-CORNELL AIDS CLINICAL TRIALS UNIT
-
批准号:6488741
-
项目类别:
-
资助金额:$146.63万
-
财政年份:2000
-
负责人:Scott M Hammer
-
依托单位:
COLUMBIA-ADARC-CORNELL AIDS CLINICAL TRIALS UNIT
-
批准号:7150728
-
项目类别:
-
资助金额:$145.3万
-
财政年份:2000
-
负责人:Scott M Hammer
-
依托单位:
海外基金