Columbia Integrated Training Program in Infectious Disease Research

描述(由申请人提供)：这是哥伦比亚大学医学中心(CUMC)修订后的传染病博士后培训补助金申请，标题为“哥伦比亚传染病研究综合培训计划(TP-IDR)”。根据多重PI NIH模式，Scott Hammer博士和Franklin Lowy博士将担任首席研究员(PI)。两人都是老牌调查人员，具有互补的研究兴趣，并长期致力于培训新的调查人员。这项提议的目标是培养具有医学博士学位、医学博士学位或博士学位的博士后研究员，他们注定要从事学术传染病事业。跨学科项目旨在为成功开展转化性研究提供必要的技能，无论这项研究主要是基础研究还是临床/流行病学研究。最近微生物基因组学和生物医学信息学领域的巨大进步，以及这些快速发展的工具在翻译研究中的潜在应用，需要重新评估我们培训新研究人员的方法。CUMC聘请了一些世界级的研究人员(例如，转换免疫学中心主任Megan Sykes博士；流行病学主席Sandro Galea博士；微生物学和免疫学主席Sankar Ghosh博士；社会医学科学主席Lisa Metsch博士)，这增加了CUMC在传染病、病原体发现(感染与免疫中心主任Ian Lipkin博士)和生物医学信息学(George Hlipcsak博士，主席)方面的现有优势，使我们能够构建一个能够满足我们正在经历的翻译研究变革时代的需求和挑战的培训计划。Hammer博士和Lowy博士将共同主持一个执行指导委员会，该委员会将作为管理机构。招聘和录取小组委员会将确保我们的申请者人才库强大和多样化。成熟的和初级调查人员的动态组合已经聚集在一起，形成了一支紧密联系、敬业的教职员工队伍。被选中参加TP-IDR的受训人员将可以选择实验室研究项目或临床/流行病学研究项目，并可以选择获得流行病学或生物医学信息学硕士学位。授课会议和新的TP-IDR开发的研讨会系列将补充教育经验。指导、培训、职业发展和双向反馈将是彻底的。内部和外部咨询委员会将协助监督整个计划。制度支持力度大、基础广。微生物基因组学和发病机制与临床调查、流行病学和国际卫生的交叉，以及生物医学信息学的交叉进步形成了TP-IDR的概念愿景。这个项目将使我们能够培养未来的学术传染病领导者。

DESCRIPTION (provided by applicant): This is a revised application from the Columbia University Medical Center (CUMC) for a post-doctoral training grant in Infectious Diseases entitled "Columbia Integrated Training Program in Infectious Disease Research (TP-IDR)". Drs. Scott Hammer and Franklin Lowy will serve as principal investigators (PIs) under the multiple PI NIH model. Both are established investigators with complementary research interests and longstanding commitments to the training of new investigators. The goal of this proposal is to train post-doctoral fellows with MD, MD-PhD, or PhD degrees who are destined for academic infectious disease careers. The interdisciplinary program is designed to provide the necessary skillset to successfully pursue translational research whether this research be primarily basic or clinical/epidemiological. The recent dramatic advances in the fields of microbial genomics and biomedical informatics and the potential application of these rapidly evolving tools to translational research has necessitated a reappraisal of our approach to training new investigators. The recruitment to CUMC of a number of world class investigators (e.g., Dr. Megan Sykes, Director of the Center for Translational Immunology; Dr. Sandro Galea, Chair of Epidemiology; Dr. Sankar Ghosh, Chair of Microbiology & Immunology; Dr. Lisa Metsch, Chair of Sociomedical Sciences) add to the existing strengths of CUMC in Infectious Diseases, pathogen discovery (Dr. Ian Lipkin, Director of the Center for Infection and Immunity) and Biomedical Informatics (Dr. George Hripcsak, Chair) and have allowed us to construct a Training Program that can meet the needs and challenges of the transformative era in translational research which we are experiencing. Drs. Hammer and Lowy will co-chair an Executive Steering Committee that will serve as the governing body. A Recruitment and Admissions Subcommittee will insure that our applicant pool is strong and diverse. A dynamic mix of well-established and junior investigators has been assembled to form a close-knit, dedicated faculty. Trainees selected to the TP-IDR will have a choice of laboratory-based or clinical/epidemiological-based research projects and will have the option of obtaining a Masters degree in either Epidemiology or Biomedical Informatics. Didactic conferences and a new, TP-IDR developed seminar series will complement the educational experience. Mentorship, training, career development and bidirectional feedback will be thorough. Internal and External Advisory Committees will assist with oversight of the entire program. Institutional support is strong and broad-based. The intersection of microbial genomics and pathogenesis with clinical investigation, epidemiology and international health, along with the cross-cutting advances in biomedical informatics form the conceptual vision of the TP-IDR. This program will permit us to train the academic Infectious Disease leaders of the future.