Columbia Integrated Training Program in Infectious Disease Research

简介（由申请人提供）：这是哥伦比亚大学医学中心（CUMC）关于传染病博士后培训资助的修订申请，题为“哥伦比亚传染病研究综合培训计划（TP-IDR）”。Drs。Scott Hammer和Franklin Lowy将在多个PI NIH模型下担任首席研究员（PI）。两者都是具有互补研究兴趣和长期致力于培训新研究人员的既定研究人员。本项目旨在培养具有医学博士学位、医学博士学位或博士学位的博士后，从事传染病学术研究。该跨学科项目旨在为成功进行转化研究提供必要的技能，无论该研究主要是基础研究还是临床/流行病学研究。最近微生物基因组学和生物医学信息学领域的巨大进步以及这些快速发展的工具在转化研究中的潜在应用，使我们有必要重新评估我们培养新研究人员的方法。中国医学中心引进了一批世界一流的研究人员（如：转化免疫学中心主任Megan Sykes博士、流行病学主任Sandro Galea博士、微生物学与免疫学主任Sankar Ghosh博士、微生物学与免疫学主任Sankar Ghosh博士、免疫学主任sanro Galea博士、免疫学主任Sankar Ghosh博士等）。Lisa Metsch博士，社会医学科学主席)增加了CUMC在传染病，病原体发现（Ian Lipkin博士，感染和免疫中心主任）和生物医学信息学（George Hripcsak博士，主席）方面的现有优势，并使我们能够建立一个培训计划，以满足我们正在经历的转化研究变革时代的需求和挑战。Drs。哈默和洛伊将共同主持一个执行指导委员会，该委员会将作为管理机构。招聘和招生小组委员会将确保我们的申请人池是强大的和多样化的。一个动态组合的成熟和初级研究人员已经组装形成一个紧密联系，专门的教师。入选TP-IDR的学员将可以选择实验室或临床/流行病学研究项目，并可选择获得流行病学或生物医学信息学硕士学位。教学会议和TP-IDR开发的新系列研讨会将补充教育经验。指导、培训、职业发展和双向反馈将是全面的。内部和外部咨询委员会将协助监督整个项目。体制支持强大而基础广泛。微生物基因组学和发病机制与临床调查、流行病学和国际卫生的交叉，以及生物医学信息学的交叉进展，构成了TP-IDR的概念愿景。这个项目将使我们能够培养未来传染病领域的学术领袖。

DESCRIPTION (provided by applicant): This is a revised application from the Columbia University Medical Center (CUMC) for a post-doctoral training grant in Infectious Diseases entitled "Columbia Integrated Training Program in Infectious Disease Research (TP-IDR)". Drs. Scott Hammer and Franklin Lowy will serve as principal investigators (PIs) under the multiple PI NIH model. Both are established investigators with complementary research interests and longstanding commitments to the training of new investigators. The goal of this proposal is to train post-doctoral fellows with MD, MD-PhD, or PhD degrees who are destined for academic infectious disease careers. The interdisciplinary program is designed to provide the necessary skillset to successfully pursue translational research whether this research be primarily basic or clinical/epidemiological. The recent dramatic advances in the fields of microbial genomics and biomedical informatics and the potential application of these rapidly evolving tools to translational research has necessitated a reappraisal of our approach to training new investigators. The recruitment to CUMC of a number of world class investigators (e.g., Dr. Megan Sykes, Director of the Center for Translational Immunology; Dr. Sandro Galea, Chair of Epidemiology; Dr. Sankar Ghosh, Chair of Microbiology & Immunology; Dr. Lisa Metsch, Chair of Sociomedical Sciences) add to the existing strengths of CUMC in Infectious Diseases, pathogen discovery (Dr. Ian Lipkin, Director of the Center for Infection and Immunity) and Biomedical Informatics (Dr. George Hripcsak, Chair) and have allowed us to construct a Training Program that can meet the needs and challenges of the transformative era in translational research which we are experiencing. Drs. Hammer and Lowy will co-chair an Executive Steering Committee that will serve as the governing body. A Recruitment and Admissions Subcommittee will insure that our applicant pool is strong and diverse. A dynamic mix of well-established and junior investigators has been assembled to form a close-knit, dedicated faculty. Trainees selected to the TP-IDR will have a choice of laboratory-based or clinical/epidemiological-based research projects and will have the option of obtaining a Masters degree in either Epidemiology or Biomedical Informatics. Didactic conferences and a new, TP-IDR developed seminar series will complement the educational experience. Mentorship, training, career development and bidirectional feedback will be thorough. Internal and External Advisory Committees will assist with oversight of the entire program. Institutional support is strong and broad-based. The intersection of microbial genomics and pathogenesis with clinical investigation, epidemiology and international health, along with the cross-cutting advances in biomedical informatics form the conceptual vision of the TP-IDR. This program will permit us to train the academic Infectious Disease leaders of the future.