Columbia Integrated Training Program in Infectious Disease Research

描述（由申请人提供）：这是哥伦比亚大学医学中心（CDC）的修订申请，用于传染病博士后培训补助金，题为“哥伦比亚传染病研究综合培训计划（TP-IDR）"。Scott Hammer博士和富兰克林Lowy博士将担任多PI NIH模型下的主要研究者（PI）。两者都是成熟的研究人员，具有互补的研究兴趣，并长期致力于培训新的研究人员。该提案的目标是培养具有MD，MD-PhD或PhD学位的博士后研究员，他们注定要从事学术传染病职业。跨学科计划旨在提供必要的技能，以成功地进行转化研究，无论这项研究是主要的基础或临床/流行病学。最近在微生物基因组学和生物医学信息学领域取得的巨大进展以及这些快速发展的工具在转化研究中的潜在应用，使我们有必要重新评估培训新研究人员的方法。征聘了一些世界级的调查员（例如，Megan Sykes博士，转化免疫学中心主任; Sandro Galea博士，流行病学主席; Sankar Ghosh博士，微生物学和免疫学主席;丽莎梅奇博士，社会医学科学主席）增加了传染病，病原体发现，（感染和免疫中心主任Ian Lipkin博士）和生物医学信息学（乔治Hripcsak博士，主席），并使我们能够建立一个培训计划，可以满足我们正在经历的转化研究变革时代的需求和挑战。Hammer博士和Lowy博士将共同主持一个执行指导委员会，该委员会将作为管理机构。一个招聘和招生小组委员会将确保我们的申请人库是强大的和多样化的。一个充满活力的组合，建立和初级调查人员已经组装，形成一个紧密联系，敬业的教师。被选中的TP-IDR的学员将有一个基于实验室或临床/流行病学为基础的研究项目的选择，并将获得流行病学或生物医学信息学硕士学位的选择。教学会议和一个新的，TP-IDR开发的系列研讨会将补充教育经验。指导、培训、职业发展和双向反馈将是彻底的。内部和外部咨询委员会将协助监督整个计划。机构支助是强有力的，基础广泛。微生物基因组学和发病机制与临床研究、流行病学和国际卫生的交叉，沿着生物医学信息学的交叉进展，形成了TP-IDR的概念愿景。该计划将使我们能够培养未来的学术传染病领导人。

DESCRIPTION (provided by applicant): This is a revised application from the Columbia University Medical Center (CUMC) for a post-doctoral training grant in Infectious Diseases entitled "Columbia Integrated Training Program in Infectious Disease Research (TP-IDR)". Drs. Scott Hammer and Franklin Lowy will serve as principal investigators (PIs) under the multiple PI NIH model. Both are established investigators with complementary research interests and longstanding commitments to the training of new investigators. The goal of this proposal is to train post-doctoral fellows with MD, MD-PhD, or PhD degrees who are destined for academic infectious disease careers. The interdisciplinary program is designed to provide the necessary skillset to successfully pursue translational research whether this research be primarily basic or clinical/epidemiological. The recent dramatic advances in the fields of microbial genomics and biomedical informatics and the potential application of these rapidly evolving tools to translational research has necessitated a reappraisal of our approach to training new investigators. The recruitment to CUMC of a number of world class investigators (e.g., Dr. Megan Sykes, Director of the Center for Translational Immunology; Dr. Sandro Galea, Chair of Epidemiology; Dr. Sankar Ghosh, Chair of Microbiology & Immunology; Dr. Lisa Metsch, Chair of Sociomedical Sciences) add to the existing strengths of CUMC in Infectious Diseases, pathogen discovery (Dr. Ian Lipkin, Director of the Center for Infection and Immunity) and Biomedical Informatics (Dr. George Hripcsak, Chair) and have allowed us to construct a Training Program that can meet the needs and challenges of the transformative era in translational research which we are experiencing. Drs. Hammer and Lowy will co-chair an Executive Steering Committee that will serve as the governing body. A Recruitment and Admissions Subcommittee will insure that our applicant pool is strong and diverse. A dynamic mix of well-established and junior investigators has been assembled to form a close-knit, dedicated faculty. Trainees selected to the TP-IDR will have a choice of laboratory-based or clinical/epidemiological-based research projects and will have the option of obtaining a Masters degree in either Epidemiology or Biomedical Informatics. Didactic conferences and a new, TP-IDR developed seminar series will complement the educational experience. Mentorship, training, career development and bidirectional feedback will be thorough. Internal and External Advisory Committees will assist with oversight of the entire program. Institutional support is strong and broad-based. The intersection of microbial genomics and pathogenesis with clinical investigation, epidemiology and international health, along with the cross-cutting advances in biomedical informatics form the conceptual vision of the TP-IDR. This program will permit us to train the academic Infectious Disease leaders of the future.