Novel extremophilic metalloprotease for consumer product application

这个博士项目将从极端微生物中鉴定和鉴定新型蛋白酶，用于工业合作者联合利华感兴趣的工艺和产品。学生将有机会与爱丁堡基因组铸造厂工作，这是一个最先进的合成生物学设施，具有令人兴奋的设计，合成和组装合成DNA的能力，为酶工程开辟了新的机会。现在有大量的微生物基因组序列可供研究界使用。这是一个令人难以置信的资源，再加上DNA合成的低成本，为获得生物多样性和获得用于一系列应用的新型酶提供了巨大的机会。该项目将利用最先进的生物信息学、高通量筛选技术，并将其与先进的生物学和生物加工技术联合收割机相结合。学生还将有机会与联合利华密切互动，并作为学生群体的一部分将参加联合利华学生培训计划，研讨会和网络。

This PhD project will identify and characterise novel protease enzymes from extremophiles for use in processes and products of interest to the industrial collaborator Unilever. The student will have the opportunity to work with the Edinburgh Genome Foundry a state of the art synthetic biology facility that has the exciting capability to design, synthesize and assemble synthetic DNA, opening up new opportunities for enzyme engineering. There are now a phenomenal number of microbial genome sequences available to the research community. This is an incredible resource and coupled with the lower cost of DNA synthesis provides huge opportunities to access biological diversity and obtain novel enzymes for a range of applications. The project will utilise state-of-the-art bioinformatics, high-throughput screening technology, and combine it with advanced biological and bioprocess techniques. The student will also have the opportunity of close interactions with Unilever and as part of their student cohort will take part in Unilever student training programmes, workshops and networking.