Interactive Internet Interventions for smoking

描述（由研究者提供）：非常需要 有效的，低成本的戒烟干预措施，可以达到大 吸烟人群。基于互联网的戒烟计划可以达到 吸烟者越来越多。大约三分之一的人 是互联网用户;估计其中有800万人是吸烟者。 基于互联网的戒烟计划可以是互动的，个性化的 信息的基础上参与者的特点和利益，提供了一个高 选择的程度和灵活性，并提供来自同龄人的社会支持 和专业人士。虽然初始启动成本可能很高，但互动 互联网干预措施的维护成本很低，并提供24小时/7天服务。 获得戒烟援助。 我们将制定一个全面的互联网戒烟计划， 主要组成部分： (a)支持使用有效的药物治疗（例如， 尼古丁替代疗法和Zyban），（B）a认知行为技能 （c）社会支持（主要通过网上论坛和聊天） 房间），并在一项旨在评估 方案的影响。控制条件将是运动和营养 为互联网使用而设计的有效性证明计划（PACE+）。这个程序 作为一个可信的注意力安慰剂控制。 大约2000人将从大型工地招募， 内联网链接（和高带宽连接）到我们的网站。所有评估 将通过互联网和大部分过程数据来完成-使用 记录了各种干预要素和讨论小组的记录 并自动存储。在三个月和三个月的七天点流行率停止 6个月的随访将作为主要结果，并辅以其他 流行率和持续戒烟结果。多种学科特点 和过程措施将被视为预测或调解人。后 结果在六个月时评估，参与者将获得 对比情况，并鼓励注册。次要分析将检查 PACE+计划的有效性。设计将提供 关于低成本互联网有效性的重要实用信息 帮助吸烟者戒烟。

DESCRIPTION (provided by investigator): There is an important need for validated, low-cost smoking cessation interventions that can reach large populations of smokers. Internet-based cessation programs can reach an increasingly large number of smokers. Approximately one third of all persons are Internet users; an estimated 8 million of them are cigarette smokers. Internet-based smoking cessation programs can be interactive, personalize information based on participant characteristics and interests, provide a high degree of choice and flexibility, and provide social support from both peers and professionals. While initial start-up costs can be high, interactive Internet interventions cost little to maintain, and provide 24-hour/7-day access to smoking cessation assistance. We will develop a comprehensive Internet smoking cessation program with three major components: (a) support for the use of efficacious pharmacological therapies (e.g., nicotine replacement therapy and Zyban), (b) a cognitive-behavioral skills development, and (c) social support (primarily via on-line forums and chat rooms), and evaluate it in a randomized control trial designed to assess the impact of the program. The control condition will be an exercise and nutrition program of proven efficacy (PACE+) designed for Internet use. This program serves as a credible attention-placebo control. Approximately 2000 persons will be enrolled from large worksites that provide intranet links (and high-bandwidth connections) to our website. All assessment will be accomplished via the Internet and much of the process data--use of various intervention elements and transcripts of discussion groups--is recorded and stored automatically. Seven-day point prevalence cessation at three- and six-month follow-ups will serve as the primary outcomes, augmented by other prevalence and sustained quit outcomes. A variety of subject characteristics and process measures will be examined as predictors or mediators. After outcomes are assessed at six months, participants will be given access to the contrasting condition and encouraged to enroll. Secondary analyses will examine the effectiveness of the PACE+ program. The proposed design will provide important practical information about effectiveness of a low-cost Internet intervention to assist smokers in stopping smoking.