MENTAL HEALTH PREVENTION PROJECT: HELPING-U-GROW (HUGS)

拟议的K23指导患者导向研究职业发展奖是一个五年计划，旨在将候选人发展为独立的儿科预防干预研究人员，专注于预防市中心高危学龄前儿童和学龄儿童的行为障碍、犯罪和药物滥用。该建议通过以下各项为候选人提供培训和经验：(1)正式的课程工作；(2)参与由国家精神卫生研究所资助的P30 MH38725：早期危险行为流行病学中心赠款(预防中心)正在进行的实地研究，以及与导师/顾问Sharon Ramey博士一起在Civitan国际研究中心对纵向多地点Head Start数据集进行二次分析；(3)在早期Head Start环境中实施随机预防干预研究；以及(4)出席相关的研讨会/会议并发表演讲。K23奖项的目的是：(1)增加与长期临床预防干预临床试验有关的流行病学和生物统计学知识；(2)提高实施社区预防临床试验的技能；(3)发展评估干预措施有效性的技能。这项提案的首要目标是为候选人提交成功的NIMH R01社区预防赠款做好准备。在尼古拉斯·拉隆戈博士、C.亨德里克斯·布朗博士和菲利普·利夫博士的共同指导下，这位候选人将实施一项名为：Help-U-Growth(拥抱)的早期心理健康预防研究。采用分层随机设计，这项研究将检验以下假设：接受拥抱干预的家庭，包括基于心理健康的育儿课程，将证明亲子互动得到改善，父母压力减少。除了在早期的学前教育环境中提供以心理健康为基础的育儿课程的有效性的新信息外，这项研究还将提供关于父母压力、心理健康和亲子互动之间互动的有价值的信息。接受拥抱干预的儿童将与标准的早期启蒙课程进行比较。将对亲子互动进行录像评估。干预前和干预后的评估将包括儿童和家长措施。

The proposed K23 Mentored Patient-Oriented Research Career Development Award is a five year plan to develop the candidate into an independent pediatric prevention intervention researcher with a focus on prevention f behavior disorders, delinquency, and substance abuse in high-risk inner city preschool and school-aged children. The proposal provides the candidate with training and experience through a combination of: (1) formal course work; (2) participation in on-going field research sponsored by the National Institute of Mental Health-funded P30 MH38725: Epidemiologic Center for Early Risk Behaviors Grant (Prevention Center) and secondary analysis of a longitudinal multi-site Head Start data set at the Civitan International Research Center with mentor/consultant Dr. Sharon Ramey; (3) implementation of a randomized prevention intervention research study in an Early Head Start setting; and (4) attendance and presentations at pertinent seminars/conferences. The objectives of the K23 award are to: (1) increase epidemiologic and biostatistical knowledge as it relates to long-term clinical prevention intervention clinical trials; (2) improve skills in implementation of community-based prevention clinical trials; and (3) develop skills to evaluate the effectiveness of interventions. The overarching goal of this proposal is to prepare the candidate to submit a successful NIMH R01 community-based prevention grant. Supported by the co-mentorship of Drs. Nicholas lalongo, C. Hendricks Brown, and Philip Leaf, the candidate will implement an Early Head Start mental health prevention study entitled: Helping-U-Grow (HUGS). Using a stratified randomized design, the study will examine the following hypothesis: families who receive the HUG'S intervention, consisting of a mental health-based parenting curriculum, will demonstrate improved parent-child interaction and reduced parental stress. In addition to providing new information about the effectiveness of a mental health-based parenting curriculum in an Early Head Start setting, the study will provide valuable information about the interactions between parental stress, mental health, and parent- child interaction. Comparisons will be made between children who received HUG'S intervention versus standard Early Head Start curriculum. Videotaped assessments of the parent-child interaction will be conducted. Pre- and post intervention evaluations will include child and parent measures.