"Palladium Catalysed Annulation Reactions of Functionalised Conjunctive Reagents"
"Palladium Catalysed Annulation Reactions of Functionalised Conjunctive Reagents"
批准号:
2293532
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2016
资助国家:
英国
项目状态:
已结题
起止时间:
2016 至 --
中文摘要
制造阿片受体拮抗剂纳洛酮会导致形成小浓度的降解产物。为了了解降解过程,需要对这些降解剂进行表征。本项目旨在通过化学合成获得合成降解物,从而确定其结构,更好地了解其形成机理。
英文摘要
The manufacture of the opioid receptor antagonist Naloxone results in the formation of small concentrations of degradation products. In order to understand the degradation process, these degradants need to be characterised. This project aims to use chemical synthesis to access synthetic degradants, so that their structure can be confirmed and their mechanism of formation can be better understood
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