课题基金 / 基金详情

Imaging and Morphology

Imaging and Morphology
成像和形态学
批准号:
6710906
负责人:
David J. Lim
金额:
$15.65万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-07-01 至 2008-06-30

项目摘要

项目成果

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中文摘要
翻译
分子生物学和基因组学的最新进展使科学家能够同时分析数千个基因的表达,而成像技术的进步,如共聚焦显微镜,为蛋白质的高分辨率定位增加了新的维度。HeI致力于为其科学家提供最先进的形态学和成像能力,建立了活体成像中心、先进电子显微镜阿曼森中心和人类颞骨组织病理学 实验室。目前,10名高校研究人员在他们的研究中广泛使用了成像技术。提供形态成像服务和培训的中央成像和形态核心的供应,不仅将提高效率、生产力和协作,而且还将使那些不使用先进成像技术的调查人员能够开始使用这些资源。成像和形态核心旨在为高等学校的科学家提供最先进的形态学和显微镜服务,以提高生产率,鼓励合作,并设定新的研究方向。定期介绍研究成果和讨论成像领域的进展将有助于实现这些目标。该中心还将为高等教育科学界提供形态学、共聚焦显微镜和电子显微镜领域的培训和技术支持。核心人员将负责所有成像设备的定期检查和维护,以便 使其处于最佳工作状态。核心还将为调查人员提供一个安全存储数字图像的数据库。
英文摘要
Recent advances in molecular biology ,and genomics have enabled scientists to analyze simultaneons expression of thousands of genes, while advances in imaging technologies, such as confocal microscopy have added new dimensions to high-resolution localization of proteins. HEI is committed to providing its scientist with state-of-the-art morphology and imaging capabilities as evidenced by the establishment of the Intravital Imaging Center, the Ahmanson Center of Advanced Electron Microscopy and the Human Temporal Bone Histopathology Laboratory. Currently 10 HEI investigators make extensive use of imaging technologies in their research. Availability of a central Imaging and Morphology Core that provides morphology imaging services and training would not only enhance efficiency, productivity and collaborations, but would also allow those investigators not using advanced imaging technologies to begin using such resources. The Imaging and Morphology Core aims to provide state-of-the-art morphology and microscopy services to HEI scientists, in order to improve productivity, encourage collaboration and set new research directions. Regularly scheduled presentations of research results and discussions about advances in the field of imaging will help to realize these aims. The Core will also provide training and technical support in the areas of morphology, confocal microscopy and electron microscopy to the HEI scientific community. The Core personnel will be responsible for regular inspection and maintenance of all imaging equipment in order to keep them in optimal working condition. The Core will also provide investigators with a database for the secure storage of digital images.
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Role of Spiral Ligament Fibrocytes in Immune-Mediated Inner Ear Damage
  • 批准号:
    8667522
  • 项目类别:
  • 资助金额:
    $6.47万
  • 财政年份:
    2011
  • 负责人:
    David J. Lim
  • 依托单位:
Role of Spiral Ligament Fibrocytes in Immune-Mediated Inner Ear Damage
  • 批准号:
    8306773
  • 项目类别:
  • 资助金额:
    $22.13万
  • 财政年份:
    2011
  • 负责人:
    David J. Lim
  • 依托单位:
Role of Spiral Ligament Fibrocytes in Immune-Mediated Inner Ear Damage
  • 批准号:
    8181198
  • 项目类别:
  • 资助金额:
    $27.03万
  • 财政年份:
    2011
  • 负责人:
    David J. Lim
  • 依托单位:
Role of Spiral Ligament Fibrocytes in Immune-Mediated Inner Ear Damage
海外基金