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中文摘要
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描述(由申请人提供):将于6月7日至8日在佛罗里达州圣彼得海滩举行的2007年“中耳炎最新进展研究会议”将是由众议院耳研究所、匹兹堡大学医学中心耳鼻喉科共同主办并由NIDCD资助的四年一次的系列会议中的第九次。这些会议的目的是通过交流与中耳炎(OM)相关的最新发现和进展以及这种疾病病因学的分子机制,促进我们的知识和生物医学研究的进展。OM研究是一个迅速扩展的领域,开始涵盖各种学科,特别是遗传学,微生物学,免疫学,分子生物学和疫苗学。对先天免疫、Toll样受体、信号通路和生物膜作用的研究无疑将产生可能具有重要转化研究和临床应用的结果。 由于OM研究领域的多学科性质,这些会议提供了一个信息交流的场所,最终将导致在分子水平上了解这种疾病,并为OM治疗方案和疫苗的快速发展铺平道路。在以前的会议上,科学贡献来自流行病学,OM病原体的微生物学,免疫学,分子和细胞发病机制,动物模型和疫苗开发等学科。第九届研究会议(和研讨会)有望与各种多学科团体进行类似水平的互动,并介绍新的和新兴的研究领域。前八届会议的标志是他们能够汇集对该领域的发展和理解OM至关重要的学科和专业。这些会议的另一个共同点是,它们不断吸引来自微生物学,分子和细胞生物学,免疫学,流行病学等不同领域的年轻研究人员-这是一个关键因素,考虑到管理和治疗OM的任何期望无疑都将通过协调一致的多学科努力来实现。
英文摘要
DESCRIPTION (provided by applicant): The 2007 "Research Conference in Recent Advances in Otitis Media", to be held on June 7-8, in St. Pete Beach, Fl will be the ninth of a series of quadrennial conferences co-sponsored by the House Ear Institute, the Department of Otolaryngology of the University of Pittsburgh Medical Center and funded by the NIDCD. The purpose of these conferences has been to advance our knowledge and to facilitate progress in biomedical research through the exchange of current findings and advancements related to otitis media (OM), and the molecular mechanisms underlying the etiology of this disorder. OM research is a rapidly expanding field that is beginning to encompass a wide variety of disciplines, particularly genetics, microbiology, immunology, molecular biology and vaccinology. Research into the role of innate immunity, Toll-like receptors, signaling pathways, and biofilms will undoubtedly produce results that may have important translational research and clinical applications. Because of the multidisciplinary nature of the OM research field, these conferences provide a venue for the exchange of information that will ultimately lead to the understanding of this disease at the molecular level and pave the way for the rapid development of treatment options and vaccines for OM. Scientific contributions at previous conferences have come from such disciplines as epidemiology, microbiology of OM pathogens, immunology, molecular and cellular pathogenesis, animal models, and vaccine development. The ninth research conference (and symposium) holds promise into delivering a similar level of interaction with various multidisciplinary groups and introducing new and emerging areas of research. The hallmark of the previous eight conferences has been their ability to draw together the disciplines and specialties essential to the advancement of the field and understanding OM. Another point that these conferences have in common is that they continuously attract young investigators from such varied fields as microbiology, molecular and cellular biology, immunology, epidemiology, etc - a critical factor, considering that any expectations in managing and treating OM will undoubtedly come through a concerted and multidisciplinary effort.
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会议论文
Role of Spiral Ligament Fibrocytes in Immune-Mediated Inner Ear Damage
  • 批准号:
    8667522
  • 项目类别:
  • 资助金额:
    $6.47万
  • 财政年份:
    2011
  • 负责人:
    David J. Lim
  • 依托单位:
Role of Spiral Ligament Fibrocytes in Immune-Mediated Inner Ear Damage
  • 批准号:
    8306773
  • 项目类别:
  • 资助金额:
    $22.13万
  • 财政年份:
    2011
  • 负责人:
    David J. Lim
  • 依托单位:
Role of Spiral Ligament Fibrocytes in Immune-Mediated Inner Ear Damage
  • 批准号:
    8181198
  • 项目类别:
  • 资助金额:
    $27.03万
  • 财政年份:
    2011
  • 负责人:
    David J. Lim
  • 依托单位:
Role of Spiral Ligament Fibrocytes in Immune-Mediated Inner Ear Damage
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: