CORE--BIOENGINEERING

俄勒冈州听力核心生物工程核心(核心1)将支持6名听力核心用户和4名合作研究人员。生物工程核心的目的是提供工程和软件专业知识，并提供用户项目所需的某些动物的电生理特征。工程师将设计和制造定制的电子和机械设备，以解决实验和数据采集问题。计算机程序员将编写计算机软件(例如Lab View虚拟仪器)来满足用户的实验需求。工程师和工程师承担的项目 程序员将扩展核心用户的资助工作，并鼓励用户之间的协作学习。程序员将帮助创建公共数据库，允许用户之间共享实验数据。此外，将有一名电生理学技术人员测量(在小鼠、豚鼠或沙鼠身上)听性脑干反应、耳蜗复合动作电位、失真产物耳声发射和耳蜗内电位。这位技术人员的一项重要活动将是表征由uchC Mouse分子遗传学核心培育的突变小鼠的耳蜗功能状态。至于工程师和程序员，技术人员将与核心用户合作，延长支持的R01的工作时间，并加强协作研究。

The Oregon Hearing Core (OHCC) Bioengineering Core (Core 1) will support six of the OHCC users and four collaborating investigators. The purpose of the Bioengineering core is to provide engineering and software expertise and to provide electrophysiological characterization of certain animals needed in projects of the users. In engineer will design and build custom electronic and mechanical devices that solve experimental and data acquisition problems. A computer programmer will write computer software (e.g. a Lab View virtual instrument) to address the experimental needs of the users. Projects undertaken by engineer and programmer will extend the funded work of the core users and stimulate collaborative studies between users. The programmer will help create common data bases that would allow sharing of experimental data among users. In addition, an electrophysiology technician will be available to measure (in mice, guinea pigs or gerbils) auditory brainstem responses, cochlear compound action potentials, distortion product otoacoustic emissions, and endocochlear potentials. An important activity of the technician will be to characterize the functional status of the cochlea in mutant mice produced by the OHCC Mouse Molecular Genetics Core. As for the engineer and programmer, the technician will work with Core users to extend work on supported R01s and enhance collaborative studies.