Tcr Vbeta Repertoire Of T Lymphocytes-patient affect- Bi
Tcr Vbeta Repertoire Of T Lymphocytes-patient affect- Bi
批准号:
6826921
负责人:
ROBERT B. NUSSENBLATT
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
鸟枪状视网膜脉络膜病变是一种慢性炎症性疾病的眼睛,与假定的自身免疫性基础。有很强的HLA相关性(HLA-A29)。我们已经开始研究患者和对照组中T细胞受体β链可变区的库。该分析旨在表征自身免疫识别及其调节的中心步骤,促进对这种疾病中自身反应性T细胞克隆扩增幅度的研究。所有患者均已入选本研究。我们正在获得适当的HLA匹配对照的全部补充。目前尚无结果。
英文摘要
Birdshot retionchoroidopathy is a chronic inflammatory disease of the eye,with a presumed autoimmune basis. There is a strong HLA association (HLA-A29). We have begun to study the repertoire of the variable region of the beta chain of the T-cell receptor in patients and controls. The analysis is directed to characterize the central steps of autoimmune recognition and its regulation, facilitating the study of the magnitude of autoreactive T cell clonal expansion in this disease. All of the patients have been recruited for this study. We are in the process of obtaining the full complement of appropriate HLA matched controls. No results are available as of yet.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Anti Tac Antibody Treatment in Behcet's Disease
-
批准号:6227961
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Biology/Immunology Of Corneal Epithelial Stem Cells
-
批准号:6507406
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Nucleotide Polymorphisms In Primary Intraocular Lymphoma
-
批准号:6507404
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Vegf (in Situ Macular Edema & Uveitis
-
批准号:6507390
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
The Use Of An Anti-il2 Receptor Antibody In The Treatmen
-
批准号:6507392
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Behcet
-
批准号:6432482
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Single Nucleotide Polymorphisms In Intraocular Lymphoma
-
批准号:6968559
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
cDNA Microarrays In Gene Expression Of Uveitis Patients
-
批准号:6968560
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Humanized Anti-tac in the Treatment of Uveitis
-
批准号:6968519
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Primary Intraocular Lymphoma and Animal Models
-
批准号:7594071
-
项目类别:
-
资助金额:$2.6万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Humanized Anti-Tac in the treatment of uveitis
-
批准号:6227959
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Humanized Anti-tac In The Treatment Of Uveitis
-
批准号:6826740
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Cdna Microarrays In Gene Expression Of Uveitis Patients
-
批准号:6507405
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Vegf (in Situ Macular Edema & Uveitis
-
批准号:6672767
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Diagnosis And Treatment Of Ocular Inflammatory Disease (
-
批准号:7321820
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Use Of Cdna Microarrays In Gene Expression Of Uveitis Pa
-
批准号:7322367
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Treatment of choroidal subretinal neovascularization wit
-
批准号:7322465
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Use Of Cdna Microarrays In Gene Expression Of Uveitis Patients
-
批准号:7594072
-
项目类别:
-
资助金额:$5.19万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
Humanized Anti-tac In The Treatment Of Uveitis
-
批准号:7594064
-
项目类别:
-
资助金额:$44.13万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
VEGF (in situ macular edema & uveitis
-
批准号:6432481
-
项目类别:
-
资助金额:$0.0万
-
财政年份:--
-
负责人:ROBERT B. NUSSENBLATT
-
依托单位:
海外基金