A DATABASE OF IOL POSITION AND BEHAVIOR

说明(申请人提供)由首席调查员开发的高分辨率MRI技术，提供无与伦比的图像对比度，是非侵入性的，允许在任何期望的平面上获取图像而不会模糊视力，并提供调节期间和静止调节期间人工晶状体/晶体位置相对于眼内结构的无失真的在体可视化；这些信息不能通过任何其他方法获得。这项研究的最终目标是建立一个生物统计学数据库，结合从人工晶状体患者获得的MRI图像和Scheimpflg图像获得的测量结果，并提供与眼内结构相关的人工晶状体放置和调节行为的详细描述-包括各种类型人工晶状体的成功和不成功的手术结果。第一阶段的具体目标包括：1)收集单眼人工晶状体植入术患者完整眼的调节MRI数据，并测量眼前段解剖中的调节及年龄相关变化；2)收集对侧眼的MRI相应数据，并测量眼前段解剖及人工晶状体位置、倾斜(在多个平面)和偏心方面的调节及年龄相关变化；以及3)将完整眼的MR测量与我们现有的MR测量相结合，并将这些数据与现有的Scheimpflg数据进行比较。

DESCRIPTION (provided by applicant) The high-resolution MRI techniques developed by the Principal Investigator, offer unsurpassed image contrast, are non-invasive, permit the acquisition of images in any desired plane without obscuring vision, and provide undistorted in vivo visualization of the IOL/crystalline lens position in relation to the intraocular structures during accommodation and with accommodation at rest; this information cannot be obtained by any other method. The ultimate goal of this study is to produce a biometric database combining measurements obtained from MRI images and Scheimpflug images acquired from IOL patients and provide a detailed description of IOL placement and accommodative behavior in relation to the intraocular structures - including both successful and unsuccessful surgical outcomes from a variety of IOL types. The Phase I specific aims include: 1) collecting accommodative MRI data from the intact eye of cataract patients with monocular IOL implantation and measuring accommodative and age-related changes in the anterior segment anatomy; 2) collecting MRI corresponding data, from contralateral eye and measuring accommodative and age-related changes in both anterior segment anatomy and IOL position, tilt (in multiple planes) and decentration; and 3) combining the MR measurements obtained from the intact eye with our existing MR measurements and comparing these data with existing Scheimpflug data.