Continuous Intraocular Pressure Sensing System

持续监测眼内压将是眼内压管理的一个重大进展。 昏迷病人。连续监测将允许临床医生检测和量化进行性视野丧失患者的昼夜波动。通过优化IOP的控制，将减轻视网膜神经节细胞死亡，随后的视野恶化将不太可能，并且患者将具有增强的视觉功能并遭受较少的残疾。 Creare建议证明连续眼压传感器在需要白内障摘除术的青光眼患者中的可行性。所提出的创新是一种压力传感器，该压力传感器由包含在密封的、生物相容的结构内的敏感位移传感器组成，该结构可以植入需要透镜植入物的患者的眼睛中。无源谐振植入式换能器以取决于眼内压的频率从患者体外的检测器线圈吸收RF能量。连续的测量值被收集和存储，以供主治医生稍后分析。 Creare团队拥有成功开发眼内压传感器所需的所有领域的专业知识，包括微型设备的设计和制造，生物医学工程和青光眼护理的临床方面。

Continuous monitoring of intraocular pressure would be a significant advance in management of glaucomateous patients. Continuous monitoring would allow the clinician to detect and quantify diurnal fluctuations in patients with progressive visual field loss. By optimizing control of lOP, retinal ganglion cell death will be mitigated, subsequent visual field deterioration will be less likely, and patients will have enhanced visual function and suffer less disability. Creare proposes to demonstrate the feasibility of a continuous intraocular pressure sensor in glaucoma patients who require cataract extraction. The innovation proposed is a pressure sensor that consists of a sensitive displacement transducer contained within a hermetic, biocompatible structure that can be implanted in the eye of a patient who requires a lens implant. The passive, resonant, implanted transducer absorbs RF energy from a detector coil outside of the patient at a frequency that is dependent on the intraocular pressure. Continuous measurements are collected and stored for later analysis by an attending physician. The Creare team has expertise in all of the areas required for the successful development of the intraocular pressure sensor, including the design and fabrication of microdevices, biomedical engineering, and clinical aspects of glaucoma care.