NICOTINE DEPENDENCE AMONG US YOUTHS

描述（改编自申请人摘要）：本提案要求 四年的支持（411/00-3131104），以研究流行病学， 和尼古丁依赖的风险因素在全国纵向样本中， 美国18至24岁青少年的国家纵向研究 健康（添加健康）（Resnick等人，1997; Udry，1998）。请拨资金用于 涵盖纳入关于尼古丁依赖的额外访谈数据， 在下一波数据中未确定的假设风险因素 将于2000年进行的第三波调查（Wave III Survey 2000）。 本研究有三个具体目的：（1）描述流行病学 尼古丁依赖的自然史和吸烟的其他方面 行为，特别是终生吸烟，每日吸烟和吸烟量， 在美国年轻人中。(2)确定心理和社会因素， 关联并预测吸烟开始、每日吸烟、吸烟量和 尼古丁依赖（风险因素）和降低发作风险的因素， 每日吸烟、吸烟量和尼古丁依赖（保护因素）。 (3)查明性别和族裔在以下方面的共同点和差异： 目标#1和#2 为了实现这些目标，将在第三波调查中获得更多数据， 对20 000多名18-24岁青年的健康数据收集，首次访谈 年龄在12-18岁之间。该样本构成国家代表性样本， 前7 - 12年级学生，包括一个遗传信息样本的双胞胎， 全同胞、半同胞和不相关的配对。 随着新问题的增加，关于流行病学的独特数据 尼古丁依赖将可用于全国代表性样本， 美国青少年，拥有丰富的纵向信息来源。这些数据将 由于Add Health数据作为公共数据发布， 使用数据集。 拟议的研究将产生对流行病学的独特理解， 吸烟和尼古丁依赖的自然史、相关因素和病因 在年轻人中

DESCRIPTION (Adapted from the Applicant's Abstract): This proposal requests four years of support (411/00-3131104) to study the epidemiology, correlates and risk factors for nicotine dependence in a national longitudinal sample of US youths 18 to 24 years old, the National Longitudinal Study of Adolescent Health (Add Health) (Resnick et al., 1997; Udry, 1998). Funds are requested to cover the inclusion of additional interview data on nicotine dependence and two hypothesized risk factors not previously ascertained in the next wave of data collection to be implemented in the year 2000 (Wave III Survey 2000). The proposed research has three specific aims: (1) To describe the epidemiology and natural history of nicotine dependence and other aspects of smoking behavior, in particular lifetime smoking, daily smoking and quantity smoked, among US youths. (2) To identify psychological and social factors that correlate and predict smoking onset, daily smoking, quantity smoked and nicotine dependence (risk factors) and factors that reduce the risk of onset, daily smoking, quantity smoked and nicotine dependence (protective factors). (3) To identify gender and ethnic commonalties and differences with respect to Aims #1 and #2. To achieve these aims, additional data will be obtained in the third wave of Add Health data collection on over 20,000 youth aged 18-24, first interviewed at ages 12-18. The sample constitutes a national representative sample of former 7th-12th graders, and includes a genetically informative sample of twin, full sibling, half sibling and unrelated pairs. With the addition of the new questions, unique data on the epidemiology of nicotine dependence will be available for a nationally representative sample of US youths, with a rich source of longitudinal information. These data will be available to other investigators since Add Health data are released as a public use data set. The proposed study will generate a unique understanding of the epidemiology, natural history, correlates and etiology of smoking and nicotine dependence among young people