2004 Signal Transduction by Eng. Extracel. Matrices

描述(申请人提供)：这是一个会议拨款申请，请求支持第三届戈登研究会议的信号转导工程细胞外基质。本次会议将于6月27日至7月2日在密苏里州刘易斯顿的贝茨学院举行。主席将由David Mooney博士担任，副主席将由Michael Sheetz博士担任。会议将集中讨论细胞外基质(ECM)和生长因子在修复和替换因疾病或损伤而丢失或受损的组织方面的融合作用。这次会议将强调分析和操纵这些系统的系统生物工程方法，与本系列前两次会议相比，这是会议的一个主要新组成部分。在这些背景下，将讨论最新的技术水平，未发表的信号转导研究，生长因子和细胞外基质调节细胞命运的机制，以及它们在组织再生和工程中的应用。该计划将包括口头会议(每个会议有三到四名发言者和一名讨论领袖)，以及海报会议(预计大多数参与者将提交一张海报)。按照常规标准，这次会议的规模将很小(约130人)，但与会者将被挑选出来，以确保代表学术和政府机构以及小型和大型生物技术公司的各种初级和高级调查人员参加会议。将鼓励学生和博士后研究员参加，每节课至少有一名演讲者是初级研究员。通过这种方式，会议将为发展长期的跨学科互动提供一个平台，并使学生和年轻的专业人员接触到信号转导、分子和细胞生物学、生物材料和组织工程的最新想法和机会。将作出特别努力，利用所要求的财政支助，便利妇女和少数群体出席和参加本次会议。

DESCRIPTION (provided by applicant): This is a conference grant application requesting support for the third Gordon Research Conference on Signal Transduction By Engineered Extracellular Matrices. This meeting will be held June 27-July 2, at Bates College in Lewiston, ME. The Chair will be Dr. David Mooney and the Vice-Chair will be Dr. Michael Sheetz. The conference will focus on the converging roles of the extracellular matrix (ECM) and growth factors for the repair and replacement of tissue lost or damaged due to disease or injury. Systems bioengineering approaches to analyzing and manipulating these systems will be emphasized in this meeting, and this represents a major new component of the meeting, as compared to the previous two conferences in this series. In these contexts, there will be discussion of state of the art, unpublished research in signal transduction, the mechanisms by which growth factors and the ECM regulate cell fate, and their application to tissue regeneration and engineering. The program will include oral sessions (each with three to four speakers and a discussion leader), as well as poster sessions (most participants will be expected to present a poster). The meeting will be small by conventional standards (approximately 130 participants), but participants will be selected to insure attendance by a diverse group of junior and senior investigators representing academic and government institutions, as well as small and large biotechnology companies. Students and postdoctoral fellows will be encouraged to attend, and at least one speaker in each session will be a junior investigator. In this way the meeting will provide a platform for the development of long term interdisciplinary interactions, and expose students and young professionals to the latest ideas and opportunities at the confluence of signal transduction, molecular and cellular biology, biomaterials and tissue engineering. A special effort will be made to use the financial support requested to facilitate the attendance and participation of women and minorities in this meeting.