Core--Exposure Assessment

描述（申请人提供）：暴露评估核心的主要目标是为中心内的所有研究项目提供高质量、全面和具有成本效益的暴露评估资源。第二，以研究为导向的目标是开发和评估新的方法来评估和量化儿童在城市环境中暴露于ED和其他发育毒物。 自上次申请以来，核心方案的目标保持不变，即：确定城市环境中新的发育毒物;确定和制定接触标记，以便对婴儿和儿童的环境接触情况进行精确的个人评估;通过分析环境和生物样本，量化儿童接触已知环境毒物的情况;评估和量化暴露途径;获取和储存环境和生物样本;并为中心项目中进行的所有分析提供质量保证/质量控制（QA/QC）。

Description (provided by applicant): The primary, service-oriented goal of the Exposure Assessment Core is to provide a high-quality, comprehensive and cost-effective resource in exposure assessment for all of the research projects within the Center. The secondary, research-oriented goal is to develop and evaluate new approaches to the assessment and quantification of children's exposures to EDs and other developmental toxicants in the urban environment. Objectives of the core, which remain unchanged since the previous application, are to do the following: ascertain new developmental toxicants in the urban environment; identify and develop markers of exposure that will permit precise individual assessment of environmental exposures in infants and children; quantify children's exposures to known environmental toxicants, using analyses of environmental as well as of biological samples; evaluate and quantify exposure pathways; access and store environmental and biological samples; and provide quality assurance/quality control (QA/QC) for all analyses conducted in Center projects.