Pesticide Exposure Pathways

描述(由申请人提供)：儿童易感性的暴露机制由暴露的类型和频率、特定年龄的行为以及时间和毒物动力学暴露考虑因素来定义。农药暴露途径研究项目侧重于儿童接触杀虫剂的生理和行为机制。这些详细的评估与中心的其他实地和实验室项目非常吻合。社区参与性研究项目正在通过职业外卖和饮食暴露来评估儿童接触S的机制。他们的评估与农药暴露途径项目的详细喷雾漂移和活动模式评估非常吻合。这两个项目将共同为暴露评估和风险表征核心提供信息，并为基于实验室的研究提供现实背景。该项目的结果将反馈给社区参与式研究项目，并为风险表征和社区外联和翻译核心的活动提供信息，以减少暴露。

Description (provided by applicant): Mechanisms of exposure for children's susceptibility are defined by types and frequency of exposures, age-specific behaviors, and temporal and toxicokinetic exposure considerations. The Pesticide Exposure Pathways Research Project focuses on the physical and behavioral mechanisms of children's pesticide exposures. These detailed assessments fit well with the other field and laboratory-based Center projects. The Community-Based Participatory Research Project is evaluating the mechanisms of children 's exposure through occupational takehome and dietary exposures. Their assessments fit well with the detailed spray drift and activity pattern assessments of the Pesticide Exposure Pathways Project. Together, both projects will inform the Exposure Assessment and Risk Characterization Cores and provide a real-life context for the laboratory-based studies. The results of this project will feed back to inform the Community-Based Participatory Research Project and also inform the activities of the Risk Characterization and the Community Outreach and Translation Cores to reduce exposures.