Gene Ontology Consortium

描述：(申请人提供)基因本体论(GO)联盟是模式生物数据库小组、基因组注释中心和其他积极参与基因组、基因和基因产品注释的人之间的合作。通过分享制定和采用语义标准，通过为公共数据库作出贡献，并通过向科学界免费传播我们的资源，我们促进和加强了科学家利用所有可用信息促进对人类健康和疾病的了解的能力。 GO联盟的目标是1)建立和支持分子功能、生物过程、细胞成分和序列特征的本体；2)通过模式生物数据库、基因组注释中心等支持基因组、基因和基因产品对这些本体的注释；3)通过公共数据资源提供对本体、基因产品注释和支持工具和文档的广泛开放和公开访问；4)通过主办用户会议、为GO联盟增加新的数据库组和探索创新研究来扩展我们的社区，以促进GO联盟为语义集成问题寻找实用解决方案的承诺。 这一续费申请旨在支持围棋的继续开发和使用。在本授权期内，该项目的主要扩展包括以正式的本体论语言实施GO，实现序列特征的本体论，并将GO作为统一医学语言系统(UMLS)的一个组成部分。

DESCRIPTION: (provided by applicant) The Gene Ontology (GO) Consortium is a collaboration among model organism database groups, genome annotation centers and others who are actively engaged in the annotation of genomes, genes and gene products. By sharing in the development and adoption of semantic standards, by contributing to a common data repository, and by disseminating our resources freely to the scientific community, we promote and enhance the ability of scientists to use all available information to further the understanding of human health and disease. The objectives of the GO Consortium are 1) to build and support ontologies for molecular function, biological process, cellular component and sequence features; 2) to support the annotation of genomes, genes and gene products to these ontologies by model organism databases, genome annotation centers and others; 3) to provide extensive open and public access to the ontologies, the gene product annotations and supporting tools and documentation via a common data resource and 4) extend our community through hosting Users Meetings, adding new database groups to the GO Consortium, and exploring innovative research that advances the GO Consortium's commitment to finding practical solutions to semantic integration issues. This renewal application proposes to support the continued development and use of the GO. Major extensions of the project in this granting period include the implementation of the GO in formal ontological language, the realization of an ontology for sequence features, and the inclusion of the GO as a component of the Unified Medical Language System (UMLS).