Baylor WRHR Program

描述(由申请者提供)：贝勒人力资源中心项目将极大地促进分子医学妇产科医生研究员的学术生涯发展。谨代表贝勒医学院(BCM)妇产科和德克萨斯大学(UT)安德森癌症中心(M.DAC.C)妇科肿瘤科提交本WRHR提案。贝勒/M.D.安德森WRHR处于理想的位置，在两个领先的机构和两个机构的咨询委员会拥有强大的核心资源(首席调查员Joe Leigh Simpson，项目主任Colin Bishop；M.D.Anderson首席调查员David Gershenson；贝勒：Arthur Beaudet，Bert O‘Malley，Martin Matzuk，Larry Chan，Huda Zoghbi，Dennis Bier，Baruch Brody；M.D.Anderson：Michele Pollen，Thomas Burke)。拥有世界级分子项目的初级(研究)导师已经使用设定的标准进行了鉴定。在22名患者中，6名在贝勒妇产科，3名在M.D.安德森妇科，13名在贝勒其他科室。大多数研究导师已经与贝勒妇产科积极合作。 贝勒和M.D.安德森拥有强大的妇产科候选人内部人才库，并从非常成功的贝勒BIRCWH计划中证明了在K-12学者之外招聘的能力。M.D.安德森有全国最大的妇科肿瘤学培训计划，这是一个为期四年的计划，其中包括两年的实验室研究。贝勒/M.D.安德森WRHR还将积极招聘贝勒和M.D.安德森以外的候选人，特别是少数族裔候选人。遴选步骤包括候选人拜访贝勒和M.D.安德森，选择一位导师，并与导师一起准备研究和教育计划。咨询委员会将使用确定的标准挑选学者。 每个教育计划将不仅包括在22名研究导师的指导下培养实验室调查专业知识，而且还包括a)5门必修课程/研讨会(临床研究基础：疾病的细胞和分子生物学：WRHR分子医学研讨会：WRHR/BIRCWH关于妇女健康的研讨会：伦理研讨会)，b)根据需要增加课程，c)WRHR研究会议，在会上学者们的工作受到批评，d)每年WRHR杰出演讲者，和e)每年一次西南地区WRHR所有学者的年度会议，以利用网络。定期进行的评价确保了连续的成功基准：1)在2002年年初发表同行审查摘要，2)在确定的影响因素的期刊上发表文章，3)2003年R03或私人基金会支助，最终以4)RO1提交和最终支助。一名二级(临床/学术)导师(例如妇产科主任)将为WRHR学者提供临床观点，并将他们介绍到他们所在专业的领导角色。贝勒WRHR和贝勒BIRCWH的使命是不同的。在国立卫生研究院资助的医学院中排名第五，并以其遗传资源(师资和设施)而闻名，贝勒在M.D.安德森的合作下完全有能力培训BIRCWH和WRHR学者。

DESCRIPTION (provided by applicant): The Baylor WRHR Center Program will greatly enhance academic career development for the Ob/Gyn physician investigator pursuing molecular medicine. On behalf of Baylor College of Medicine (BCM) Department of Obstetrics and Gynecology and University of Texas (UT) M.D. Anderson Cancer Center (M.DAC.C) Department of Gynecologic Oncology, this WRHR proposal is submitted. Baylor/M.D. Anderson WRHR is ideally placed, with strong core resources at two leading institutions and an Advisory Committee from both institutions (Principal Investigator Joe Leigh Simpson, Program Director Colin Bishop; M.D. Anderson Primary Investigator David Gershenson; Baylor: Arthur Beaudet, Bert O'Malley, Martin Matzuk, Larry Chan, Huda Zoghbi, Dennis Bier, Baruch Brody; M.D. Anderson: Michele Pollen, Thomas Burke). Primary (Research) Mentors with world-class molecular programs have been identified using set criteria. Of the 22, 6 are in Ob/Gyn at Baylor, 3 in Gynecologic Oncology at M.D. Anderson, and 13 in other Baylor Departments. Most research mentors already collaborate actively with Baylor Ob/Gyn. Baylor and M.D. Anderson have a strong internal pool of Ob/Gyn candidates and proven ability to recruit outside K-12 Scholars, as judged by the highly successful Baylor BIRCWH Program. M.D. Anderson has the nation's largest Gynecologic Oncology Training Program, a four-year program that includes 2 years of laboratory research. Baylor/M.D. Anderson WRHR will also aggressively recruit candidates outside Baylor and M.D. Anderson, especially minority candidates. Selection steps include candidates visiting Baylor and M.D. Anderson, selecting a mentor and with the mentor, prepare a research and educational plan. Scholars will be selected by the Advisory Committee using defined criteria. Each educational plan will include not only developing laboratory investigative expertise under one of the 22 Research Mentors, but a) 5 required courses/seminars (Fundamentals of Clinical Investigation: Cellular and Molecular Biology of Disease: WRHR Molecular Medicine Seminar: WRHR/BIRCWH Seminars in Women's Health: Ethics Symposium), b) additional courses as needed, c) WRHR research conferences, at which Scholars have their work critiqued, d) yearly WRHR Distinguished Speaker, and e) once yearly meetings of all WRHR Scholars in the Southwest to leverage networking. Regularly scheduled evaluations assure sequential benchmarks of success: 1) peer review abstracts by early year -02, 2) publications in journals of defined impact factors, 3) year -03 RO3 or private foundation support, culminating in 4) RO1 submission and eventual support. A Secondary (Clinical/Academic) Mentor (e.g., Ob/Gyn Division Director) will provide WRHR Scholars clinical perspective and introduce them into leadership roles in their subspecialty. Missions of Baylor WRHR and Baylor BIRCWH are distinct. Fifth in NIH funding among medical schools and renowned for its genetic resources (faculty and facilities), Baylor with cooperation of M.D. Anderson is fully capable of training both BIRCWH and WRHR Scholars.