Pediatric Oncology Clinical Research Training Program

描述（由申请人提供）：儿科肿瘤学家的发展 在临床研究方面训练有素的儿科肿瘤科护士 对儿童治疗方面继续取得进展至关重要 癌 本提案描述了儿科肿瘤临床研究 培训计划，由贝勒医学院的得克萨斯州儿童的 癌症中心，其结构是提供一个正式的，全面的， 多学科临床研究教育计划，将培训董事会 合格的儿科肿瘤学家谁已经完成了三年的奖学金， 博士学位-编写护士本体的设计、实现与分析 临床研究试验的所有阶段。 学员将花费一部分 他们第一年参加临床研究的核心课程， 在该年及其后的剩余时间接受进一步的临床治疗， 在五个专业培训轨道中选择一个进行研究培训 （临床药理学，神经肿瘤细胞和基因治疗，白血病或 实体瘤）。 这个精心指导的培训计划将利用 的资助（NIH-K30奖）临床科学家培训计划，以提供 一个全面的，教学性的临床研究核心课程，将作为 在五个专业领域之一的进一步培训的基础， research. 每个领域的研究经验都将量身定制 以满足学员个人的长期研究目标。 它将提供 由实验室和临床导师指导，同时提供深入的 接触临床研究过程中最重要的方面。 学员将接受临床试验设计，统计分析， 研究伦理和监管要求和指南。 此外，本发明还提供了一种方法， 在经验丰富的导师指导下，学员将设计和进行 临床试验在各自的重点领域，并将学习导师 建模所需的独特的互动，协作技能， 成功开展有效的临床试验。 因为那些完成了 这一计划将是良好的基础，在双方的基础生物学， 特别是专业领域和翻译研究技能，他们将 非常适合成为儿科肿瘤临床研究的未来领导者。

DESCRIPTION (provided by applicant): The development of pediatric oncologists and pediatric oncology nurses who are highly trained in clinical research is essential for continued progress to be made in the treatment of childhood cancer. This proposal describes a Pediatric Oncology Clinical Research Training Program, developed by Baylor College of Medicine's Texas Children's Cancer Center, that is structured to provide a formal, comprehensive, multidisciplinary clinical research educational program that will train board eligible pediatric oncologists who have completed a three year fellowship and Ph.D.-prepared ontology nurses in the design, implementation and analysis of all phases of clinical research trials. Trainees will spend a portion of their first year participating in a core curriculum in clinical research and spend the remainder of that and subsequent year(s) receiving further clinical research training in their choice of one of five specialized training tracks (clinical pharmacology, neuro-oncology cell and gene therapy, leukemia or solid tumors). This carefully mentored training program will take advantage of BCM's funded (NIH-K30 award) Clinical Scientist Training Program to provide a comprehensive, didactic clinical research core curriculum that will serve as a foundation for further training within one of the five specialized areas of research. The research experience within each of these areas will be tailored to meet the individual trainee's long-term research goals. It will provide mentorship by both a laboratory and clinical mentor' while providing in depth exposure to the most important facets of the clinical research process. Trainees will be instructed in clinical trial design, statistical analysis, research ethics and regulatory requirements and guidelines. In addition, under the tutelage of experienced mentors, trainees will design and conduct clinical trials in their respective areas of focus and will learn by mentor modeling the uniquely interactive, collaborative skills necessary to successfully develop effective clinical trials. Because trainees who complete this program will be well-grounded in both in the basic biology of their particular specialty areas and translational research skills, they will be well suited to become future leaders in pediatric oncology clinical research.