UCSF-KAISER Building Interdisciplinary Research Careers in Women's Health Program

描述（由申请人提供）：加州大学旧金山分校和研究（凯撒）凯撒司举行了一个非常成功的BIRCWH奖从2000年至2005年，培训了10名学者在各种学科谁都是目前的学术教师与成功的研究生涯。UCSF-Kaiser学者共发表了178篇科学论文，其中88篇是第一作者，11篇发表在顶级期刊上。它们拥有28项联邦赠款（10项作为PI，18项作为Co-l）和43项其他赠款（32项作为PI，11项作为Co-l），并有20项赠款金正在审查中（17项联邦补助金和3项其他补助金; 12项作为PI，8项作为Co-l）。我们建议继续和加强UCSF-Kaiser BIRCWH，招募具有卓越潜力的初级教师学者，成为专注于女性慢性疾病的成功，独立的翻译或临床研究人员。我们将我们在妇女健康方面的优势组织成10个多学科研究小组（乳腺癌;心血管疾病;补充和替代医学;痴呆症和认知功能障碍;妇女艾滋病毒;更年期和激素治疗;肥胖症;骨质疏松症和骨关节炎;疾病筛查和尿失禁）。每个团队都由高级导师（经验丰富的翻译和临床研究人员）领导，包括来自多个学科的资源学院，核心方法学家，广泛的研究资源和多个生物标本或图像库。学者将完成基础科学或临床研究的个性化教学培训，并由资深科学家指导实践经验。在与导师协商，学者将准备和每年修订培训计划，包括类似于NIH K系列提案的研究议程。每个计划都将围绕着走向独立的里程碑而建立：演讲、出版物和独立资助。每两周举行一次的妇女健康核心研讨会将涵盖妇女健康的一系列问题，每两周举行一次的正在进行的工作会议将使学者们有充足的时间对研究项目进行专家反馈。一个由妇女健康高级领导人组成的咨询委员会将挑选学者，评估该方案，并向BIRCWH领导层提供咨询意见。Deborah Grady，医学博士，公共卫生硕士，系副主任。流行病学和UCSF妇女健康临床研究中心主任将担任PI，由流行病学（Co-Pi）名誉教授Steven Cummings博士和Kaiser DOR（Co-Pi）主任Joe Selby博士协助。我们的目标是建立一个培训成功的妇女健康调查人员的国家示范资源。

DESCRIPTION (provided by applicant): UCSF and the Kaiser Division of Research (Kaiser) held a highly successful BIRCWH award from 2000 to 2005 that trained 10 Scholars in a variety of disciplines who are all currently academic faculty with successful research careers. In sum UCSF-Kaiser Scholars have published 178 scientific manuscripts, 88 as primary author and 11 in top journals. They hold 28 federal grants (10 as PI and 18 as Co-l) and 43 other grants (32 as PI and 11 as Co-l) and have 20 grants under review (17 federal and 3 other; 12 as PI and 8 as Co-l). We propose to continue and strengthen the UCSF-Kaiser BIRCWH by recruiting junior faculty Scholars with superb potential to become successful, independent translational or clinical researchers focused on chronic disease in women. We have organized our strengths in women's health into 10 Multidisciplinary Research Teams (breast cancer; cardiovascular disease; complementary and alternative medicine; dementia and cognitive dysfunction; HIV in women; menopause and hormone therapy; obesity; osteoporosis and osteoarthritis; screening for disease and urinary incontinence). Each team is lead by Senior Mentors (an experienced translational and clinical researcher) and includes Resource Faculty from multiple disciplines, Core Methodologists, extensive Research Resources and multiple Repositories of Biological Specimens or Images. Scholars will complete individualized didactic training in basic science or clinical research and practical experience mentored by senior scientists. In consultation with mentors, Scholars will prepare and annually revise a training program including a research agenda similar to NIH K-series proposals. Each plan will be built around milestones toward independence: presentations, publications and independent funding. A biweekly Core Seminar in Women's Health will cover a range of issues in women' health and a biweekly Works-in-Progress session will allow Scholars ample time for expert feedback on research projects. An Advisory Board composed of senior leaders in women's health will select Scholars, evaluate the program and advise the BIRCWH leadership. Deborah Grady, MD, MPH, Vice Chair of the Dept. of Epidemiology and Director of the UCSF Women's Health Clinical Research Center will act as PI, assisted by Drs. Steven Cummings, Emeritus Prof, of Epidemiology (Co-Pi) and Joe Selby, Director of Kaiser DOR (Co-Pi). Our goal is to create a model national resource for training successful investigators in women's health.