Incorporating Chiral Cations into Transition Metal Catalysis

手性阳离子已被广泛用作有机催化剂，但很少用作多用途和活性过渡金属的手性控制器，尽管它们具有明显的潜力。本项目利用阴离子配体将手性阳离子加入到各种主流的过渡金属催化过程中，这些过程很难通过常规手段呈现手性。我们计划调查一系列流程，并评估这一战略的更广泛可行性。

Chiral cations have been used extensively as organocatalysts but it is very rare for them to be used as chiral controller for versatile and reactive transition metals, despite the obvious potential. This project uses anionic ligands to incorporate chiral cations into various mainstream transition metal catalysed processes that are difficult to render chiral through conventional means. We plan to investigate a range of processes and assess the broader viability of this strategy.