Graduate Training in Biochemistry and Molecular Biology

描述（由申请人提供）：现代生物学正在进入一个新时代。的 多种生物体的基因组已被完全测序， 基因组规模的项目正在进行中。这些项目正在产生巨大的 潜在基因产物、RNA和蛋白质表达谱的数据库， 与基因型相关的表型和结构信息。这些信息 为前所未有的生物学洞察力提供了基础， 对生物医学研究的潜在影响。然而，至关重要的是， 培养新的科学家来利用这些生物信息。 21世纪优秀科学家的三个基本特征 世纪：1）复杂的生物化学，分子和生物学的基础知识。 细胞过程共同控制正常条件下的生理稳态， 和病态的国家2)理解和利用信息的能力 多学科发展新的生物学见解。3)的能力 有效地交流研究目标和科学发现， 口头和书面形式，其他科学家，教育工作者，立法者， 平民为了培养具备这些必要技能的个人， 几年前，我们开发了一个跨部门的博士学位。培训计划， 强调科学研究的跨学科方法，重点是 生物化学、分子和细胞生物学领域。这是第一次 延长培训补助金，部分支持学生在 程序.这个群体所代表的研究专长的深度和广度 研究人员，他们对研究生教育的承诺是根本的 为拟议的跨学科培训奠定基础。

DESCRIPTION (provided by applicant): Modern biology is entering a new era. The genomes of multiple organisms have been completely sequenced and numerous genomic scale projects are ongoing. These projects are generating vast databases of potential gene products, RNA and protein expression profiles, phenotypes linked to genotypes, and structural information. This information provides the foundation for unprecedented biological insight, which has great potential to impact on biomedical research. However, it will be critical that new scientists be trained to take advantage of this biological information. Three essential attributes will characterize excellent scientists of the 21st century: 1) A fundamental knowledge of the complex biochemical, molecular and cellular processes that together control physiological homeostasis under normal and diseased states. 2) The ability to understand and utilize information from multiple disciplines to develop new biological insights. 3) The ability to effectively communicate research objectives and scientific findings in both oral and written form, to other scientists, to educators, to legislators, and lay citizens. In order to train individuals with these necessary skills, eight years ago we developed an interdepartmental Ph.D. training program that emphasizes an interdisciplinary approach to scientific research focused on the areas of biochemistry, molecular and cellular biology. This grant is the first renewal of the training grant that partially supports the students within the program. The depth and breadth of research expertise represented by this group of researchers, and their commitment to graduate education is the underlying foundation for the proposed interdisciplinary training.