Speech Development in Children with Cerebral Palsy

描述（由申请人提供）：脑瘫（CP）是一种非进行性的、基于神经学的运动障碍综合征，通常在出生后的前18个月内诊断出来（Rosenbaum等人，2002年）。研究表明，高达88%的CP患者患有构音障碍（Achilles，1955）。构音障碍的一个重要后果是言语清晰度降低（Yorkston等人，1999年），这反过来又经常导致对社会参与和教育/职业追求的干扰。尽管有越来越多的文献研究CP儿童的粗大和精细运动发育（Hanna等人，2003; Rosenbaum等人，2002年），还没有研究检查的纵向发展的讲话，在这个人口。因此，通过自然语音进行通信的长期效果和结果是不确定的。CP儿童言语发育的研究提供了一个机会，通过识别特定的变量，有助于在构音障碍儿童的可懂度，并指定这些变量如何随时间变化沿着这些变化对可懂度的相对影响，以推进一个全面的言语可懂度理论。凯瑟琳哈斯塔德博士，是威斯康星州-麦迪逊大学的终身助理教授。她的目标是扩展她目前的研究，专注于成年人与CP，在儿童与CP的言语发展的研究。拟议的前瞻性纵向研究将收集有关语音清晰度，频谱和时间声学措施和感知/分段功能的一个队列的26名儿童与CP开始之间的年龄在24和48个月的四年期间的语音。韦斯曼中心和威斯康星州-麦迪逊大学非常适合实现职业发展计划的目标，该计划将侧重于PI获得：儿童运动发育和运动性言语障碍领域的高级内容知识;言语测量技术的专业知识，包括声学分析程序和构音障碍言语的分段表征;纵向研究设计和分析的技术专长，包括临床研究和测量的一般问题。本项目的主要导师雷肯特教授在构音障碍和言语科学方面拥有丰富的研究经验和专业知识。他将提供一对一的指导和指导，在言语发展，运动言语障碍的儿童，和声学分析程序的领域。

DESCRIPTION (provided by applicant): Cerebral palsy (CP) is a non-progressive, neurologically-based, motor impairment syndrome that is usually diagnosed within the first 18 months of life (Rosenbaum et al., 2002). Research suggests that up to 88% of those with CP have dysarthria (Achilles, 1955). One important consequence of dysarthria is reduced speech intelligibility (Yorkston et al., 1999), which in turn frequently results in interference with social participation and educational / vocational pursuits. Although there is a growing body of literature examining gross and fine motor development in children with CP (Hanna et al., 2003; Rosenbaum et al., 2002), there have been no studies examining the longitudinal development of speech in this population. Thus, long-term prognoses and outcomes for communication via natural speech are uncertain. The study of speech development in children with CP presents an opportunity to advance a comprehensive theory of speech intelligibility by identifying specific variables that contribute to intelligibility in children with dysarthria; and specifying how these variables change over time along with the relative effects of these changes on intelligibility. Katherine Hustad, Ph.D., is a tenure-track assistant professor at the University of Wisconsin - Madison. Her goal is to extend her current research, focused on adults with CP, to the study of speech development in children with CP. The proposed prospective longitudinal study will gather data regarding speech intelligibility, spectral and temporal acoustic measures and perceptual / segmental features of the speech of a cohort of 26 children with CP beginning between the ages of 24 and 48 months over a four year period. The Waisman Center and the University of Wisconsin - Madison are ideally suited to meet the goals of the career development plan, which will focus on the Pl's acquisition of: advanced content knowledge in the domains of motor development and motor speech disorders in children; technical expertise in speech measurement techniques including acoustic analysis procedures and segmental characterization of dysarthric speech; and technical expertise in longitudinal research design and analysis, including general issues in clinical investigation and measurement. The primary mentor for this project, Professor Ray Kent, has extensive research experience and expertise in dysarthria and speech science. He will provide one-on-one instruction and mentorship in the areas of speech development, motor speech disorders in children, and acoustic analysis procedures.