Stem Cell Research Training Program

描述(由申请人提供)：我们建议为干细胞生物学研究的所有方面建立一个跨学科的博士后培训计划。该项目的一个主要优势是威斯康星大学在干细胞生物学方面的一系列专业知识--从基础胚胎学到临床试验，再到伦理学和政策研究。来自发育生物学、神经科学、内分泌学、血液科学、心脏科学、生物工程和其他专业(如政策和伦理学)的博士后实习生将进入这个项目，并与适合他们感兴趣的领域的主要导师进行匹配。此外，还将有机会研究干细胞研究的伦理影响。该计划的主要方面包括：(I)建立直接对干细胞生物学感兴趣的导师委员会；(Ii)通过研讨会、杂志俱乐部、研讨会和务虚会，鼓励与参与干细胞研究的其他实验室积极互动；(Iii)参加威斯康星大学麦迪逊分校有关干细胞生物学和研究伦理的课程；以及(Iv)与校园内已成为干细胞生物学核心的关键机构进行互动，包括生物技术中心、韦斯曼中心、灵长类中心和非营利性组织Wicell。受训人员将参加一些新开发的干细胞生物学课程--从基本原理到应用。他们将意识到干细胞生物学的巨大商业意义，以及将这种潜力转化为临床试验的最新想法。调查人员的目标是在这一重要的新领域培训下一代首席调查人员。该计划中所有使用人类胚胎干细胞的实验室将继续只使用联邦批准的细胞系，特别是WA01、WA07、WA09、WA13和/或WA14。

DESCRIPTION (provided by applicant): We propose to establish an interdisciplinary postdoctoral training program for all aspects of research into the biology of stem cells. A major strength of this program is the range of expertise at University of Wisconsin in stem cell biology - from basic embryology, through clinical trials, to ethics and policy research. Postdoctoral trainees from specific areas of developmental biology, neuroscience, endocrinology, blood science, heart science, bioengineering, and other specialties such as policy and ethics will enter this program and be matched with the primary mentor appropriate for their area of interest. In addition, there will be opportunities to study the ethical implications of stem cell research. Key aspects of the program include (i) establishing mentor committees with direct interest in stem cell biology, (ii) encouraging active interactions with other laboratories involved with stem cell research through seminars, journal clubs, workshops, and retreats, (iii) attending UW-Madison courses related to stem cell biology and research ethics, and (iv) interacting with the key institutes on campus which have become central to stem cell biology, including the Biotech Center, Waisman Center, Primate Center, and the non profit organization WiCell. The trainees will participate in a number of newly developed courses in stem cell biology - from basic principles to applications. They will be made aware of the huge commercial implications of stem cell biology and the latest thinking on translating this potential into clinical trials. The investigators aim to train a future generation of principal investigators within this important new field. All laboratories in this program which work with human embryonic stem cells will continue to use only Federally-approved cell lines, specifically WA01, WA07, WA09, WA13, and/or WA14.