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中文摘要
翻译
这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金, 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的:向公众宣传和教育威斯康星大学麦迪逊分校的干细胞和再生医学研究。让教师和学生参与进来,并提供资源和想法,将干细胞和再生医学研究纳入科学教育课程。与新的(2009)华盛顿大学麦迪逊分校科学外展办公室合作,宣传该计划,帮助教师和其他人找到我们的服务,并安排访问实验室。 这是威斯康星大学麦迪逊干细胞和再生医学中心、生物技术中心、灵长类中心及其在威斯康星州的外展合作伙伴之间持续合作的努力。项目负责人是乔丹娜·列农,B.S.,她雇佣了一名学生小时工实验室经理。 2008-2009年,我们成功地在遗传学-生物技术中心为公众建立了干细胞学习实验室,为公众、4-12年级的学生、大学生、少数族裔项目、校友、退休人员和其他“终身学习者”提供服务。参观者观看介绍性演讲,提出问题,并讨论研究和当前问题。然后,由于生物安全问题,这些小组在实验室使用真实的实验室技术和设备,使用模拟细胞和培养液。他们能够观察到詹姆斯·汤姆森实验室中真实的ES和iPS细胞。(我们在早上,在小组到达之前获取活细胞。)许多小组随后参观灵长类中心,了解其在威斯康星大学麦迪逊分校干细胞历史和当前研究中的重要作用。 实验室设置在2008年初进行,第一批小组于2008年4月开始访问。到目前为止,我们的实验室体验已经吸引了1000多名参观者。我们还将这种体验带到了威斯康星州大学麦迪逊分校的科学探险,以及在路上,到了包括布朗县的农场技术日和密尔沃基县的威斯康星州博览会在内的场馆。 通过这个项目,我们还安排了威斯康星大学麦迪逊分校的干细胞和再生医学演讲者向众多观众介绍这一广阔的科学领域。我们的演讲者包括首席研究员、博士后实习生和研究生。 这个项目依赖于WNPRC公共信息官员的时间和资源,他也是干细胞和再生医学中心的大学关系专家。 该项目使用了联邦政府批准的从詹姆斯·汤姆森实验室获得的人类胚胎干细胞系。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: To inform and educate the public about stem cell and regenerative medicine research at the UW-Madison. To engage teachers and students and provide resources and ideas for incorporating stem cell and regenerative medicine studies into science education curricula. To work with the new (2009) UW-Madison Office of Science Outreach to publicize the program and help teachers and others find our service and schedule visits to the lab. This is a continuing collaborative effort among the UW-Madison Stem Cell and Regenerative Medicine Center, Biotech Center, Primate Center and their outreach partners throughout Wisconsin. The project leader is Jordana Lenon, B.S., and she employs a student hourly lab manager. In 2008-2009, we successfully set up a stem cell learning lab for the public at the Genetics-Biotechnology Center, to serve the public, students grades 4-12, college students, minority programs, alumni, retirees, and other "lifelong learners." Visitors view an introductory talk, ask questions and discuss research and current issues. Then, the groups work in a lab using real lab techniques and equipment, with simulated cells and media due to biosafety issues. They are able to observe real live ES and iPS cells from James Thomson's lab. (We acquire the live cells in the morning, before the groups arrive.) Many groups then visit the Primate Center and learn about its important role in UW-Madison stem cell history and current research. Lab setup occurred early in 2008, the first groups began visiting in April 2008. To date, our lab experiences have drawn more than 1,000 visitors. We have also taken the experience to UW-Madison's Science Expeditions, and on the road, to venues including Farm Technology Days in Brown County, and the Wisconsin State Fair in Milwaukee County. Through this project, we have also scheduled UW-Madison stem cell and regenerative medicine speakers to present to numerous audiences about this broad scientific field. Our speakers have included principal investigators, post-doctoral trainees and graduate students. This project relies on the time and resources of the WNPRC Public Information Officer, who is also a university relations specialist for the Stem Cell and Regenerative Medicine Center. This project uses federally approved human embryonic stem cell lines obtained from James Thomson's lab.
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A Lung-chip microphysiological system to model SARS-CoV-2 infection and test novel therapeutics
  • 批准号:
    10179816
  • 项目类别:
  • 资助金额:
    $116.38万
  • 财政年份:
    2020
  • 负责人:
    CLIVE Niels SVENDSEN
  • 依托单位:
A microphysiologic multicellular organ-on-chip to inform clinical trials in FTD/ALS
  • 批准号:
    10204148
  • 项目类别:
  • 资助金额:
    $80.08万
  • 财政年份:
    2020
  • 负责人:
    CLIVE Niels SVENDSEN
  • 依托单位:
A microphysiologic multicellular organ-on-chip to inform clinical trials in FTD/ALS
  • 批准号:
    10515787
  • 项目类别:
  • 资助金额:
    $79.22万
  • 财政年份:
    2020
  • 负责人:
    CLIVE Niels SVENDSEN
  • 依托单位:
A microphysiologic multicellular organ-on-chip to inform clinical trials in FTD/ALS
  • 批准号:
    10038289
  • 项目类别:
  • 资助金额:
    $82.51万
  • 财政年份:
    2020
  • 负责人:
    CLIVE Niels SVENDSEN
  • 依托单位:
国内基金
海外基金
分化肌细胞脱细胞ECM-cells sheet 3D 支架构建及其促进容积性肌组织缺损再 生修复应用及机制研究
CAFs-TAMs-tumor cells调控在HRHPV感染致癌中的作用机制研究及AI可追溯预测模型建立
  • 批准号:
    82072862
  • 项目类别:
    面上项目
  • 资助金额:
    56.0万元
  • 批准年份:
    2020
  • 负责人:
    徐云升
  • 依托单位:
S100A8/A9--Myeloid cells特异性可溶性表氧化物水解酶(sEH)基因敲除改善胰岛素抵抗的新靶点
  • 批准号:
    82070825
  • 项目类别:
    面上项目
  • 资助金额:
    53.0万元
  • 批准年份:
    2020
  • 负责人:
    徐西振
  • 依托单位:
Leader cells通过CCL5调控糖酵解及基质硬度促进结直肠癌集体侵袭的 作用机制
  • 批准号:
    81903002
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    20.5万元
  • 批准年份:
    2019
  • 负责人:
    王斐斐
  • 依托单位: