A Transtheoretical Model Group Therapy For Cocaine

描述（由申请人提供）： 在一般人群中使用避孕药是一个重大和昂贵的问题。需要针对可卡因滥用的新颖和创新的干预措施。行为改变的跨理论模型（TTM）为理解、测量和干预行为改变提供了一个全面的框架，并为药物滥用的有效治疗提供了坚实的理论基础。拟议的第一阶段研究将对基于TTM的可卡因使用者进行新颖和创新的行为团体疗法进行试点测试。 在第一阶段，研究人员将修改新开发的药物滥用团体治疗：改变阶段治疗手册（Velasquez，Maurer，Crouch & DiClemente，2001）专门针对可卡因滥用，根据TTM阶段和变化过程，制定了一份为期12次的小组干预和伴随治疗手册：六个“早期阶段”的会议针对的是变化的经验过程，六个“后期阶段”的会议针对的是变化的行为过程。第2阶段将包括一项试点试验，以评估可卡因滥用患者的TTM组治疗。将使用随机、对照、组间设计，其中可卡因滥用者（N=80）被分配至两组治疗条件之一：TTM治疗或教育/建议。参与者将通过德克萨斯大学健康科学中心精神科学研究所的物质滥用研究中心从休斯顿和周边社区招募。我们希望对可卡因使用者进行TTM治疗是可行的和可接受的，并能显著改善患者的病情。将通过客观（尿液和药物分析）和自我报告措施评估随访结果。第一阶段的研究将提供重要的理论和经验信息，为可卡因滥用者提供新的创新干预措施，并为更大的疗效试验提供基础。

DESCRIPTION (provided by applicant): Cocaine use in the general population is a significant and costly problem. Novel and innovative interventions targeting cocaine abuse are needed. The Transtheoretical Model of behavior change (TTM) offers a comprehensive framework for understanding, measuring, and intervening in behavior change and provides a strong theoretical foundation upon which effective treatments for substance abuse can be developed. The proposed Stage 1 research will pilot test a novel and innovative behavioral group therapy for cocaine users based on the TTM. In Phase 1, investigators will modify the newly developed Group Treatment for Substance Abuse: A Stages-of-Change Therapy Manual (Velasquez, Maurer, Crouch & DiClemente, 2001) to specifically target cocaine abuse resulting in a twelve-session, group intervention and accompanying therapy manual based on the TTM stages and processes of change: six "early stage" sessions targeting the experiential processes of change, and six "later stage" sessions targeting the behavioral processes of change. Phase 2 will consist of a pilot trial to evaluate the TTM group therapy with cocaine abusing patients. A randomized, controlled, between groups design will be used in which cocaine abusers (N=80) are assigned to one of two group treatment conditions: TTM therapy or Education/Advice. Participants will be recruited from Houston and surrounding communities through the Substance Abuse Research Center at the University of Texas Health Science Center Mental Sciences institute. We expect the delivery of the TTM therapy for cocaine users to be feasible and acceptable, and to produce significant patient improvement. Cocaine outcomes will be assessed via objective (urine and drug analysis) and self-report measures. This Stage I research will contribute important theoretical and empirical information concerning the promise of a new and innovative intervention for cocaine abusers, and will provide the basis for a larger efficacy trial.