12th International Symposium on Basement Membranes

描述(由申请人提供)：本R13申请是为了请求对将于2005年6月15日至18日在宾夕法尼亚州费城杰斐逊医学院举行的第12届基底膜国际研讨会(ISBM)提供部分支持。基底膜国际研讨会是一系列两年一度的活动，在欧洲、日本和美国的地点之间轮流举行。这项申请的首席调查员Jouni Uitto博士在2003年于日本举行的前一次会议上被选为本次研讨会的主席。研讨会副主席朱孟礼博士、代表皮肤科和皮肤生物学、病理学、解剖学和细胞生物学、内科/风湿科和血液科、骨科研究和遗传学以及杰斐逊医学院院长办公室的当地组织委员会协助组织了这次会议。地方组织委员会得到一个杰出的国际咨询委员会的协助。 本次研讨会的主要目的是为在与人类疾病相关的基底膜生物学和病理学等广泛领域工作的一批顶尖科学家提供一个国际论坛。第12届ISBM将由四个专题会议组成，围绕以下主题：1.基底膜的组装和结构-功能关系：2.基底膜发育和干细胞生物学；3.基底膜生物学作用的遗传学方法；和4.基底膜疾病的分子基础。这些会议共邀请了12位发言者，他们是根据他们在科学上的卓越表现和公认的与广大听众沟通的能力而被挑选出来的。此外，将从提交海报介绍的摘要中挑选18个主要由外地青年和新调查员所作的简短平台介绍。观众预计将有200-250人参加，包括广泛的知名生物化学家、结构和分子生物学家、内科科学家和临床医生。此外，我们预计该领域将有相当数量的年轻和新的研究人员--学生、博士后研究员和住院医生--参与。我们认为，本次会议是非常及时的，预计将证明其在为未来的研究团队带来跨学科方法以及加强基础科学向临床实践转化方面的有效性。从这个意义上说，这次会议将实现国家卫生研究院路线图倡议的一些目标。

DESCRIPTION (provided by applicant): This R13 application is submitted to request partial support for The 12th International Symposium on Basement Membranes (ISBM), to be held at Jefferson Medical College, Philadelphia, Pennsylvania, June 15-18, 2005. The International Symposia on Basement Membranes is a series of biennial events that rotate between sites in Europe, Japan and the United States. The Principal Investigator of this application, Dr. Jouni Uitto, was elected as the President of this Symposium in the prior meeting held in Japan, 2003. He is assisted in organizing this meeting by Dr. Mon-Li Chu, Vice President of the Symposium, and by the Local Organizing Committee representing Departments of Dermatology and Cutaneous Biology; Pathology, Anatomy and Cell Biology; Medicine/Rheumatology and Hematology; Orthopaedic Research; and Genetics; as well as the Office of the Dean of Jefferson Medical College. The Local Organizing Committee is assisted by a distinguished International Advisory Board. The principal objective of this Symposium is to provide an international forum for the cadre of premier scientists working in the broad fields of basement membrane biology and pathology, with relevance to human diseases. The 12th ISBM will consist of four thematic sessions revolving around the following topics: 1. Assembly and Structure-Function Relationships of Basement Membranes: 2. Basement Membrane Development and Stem Cell Biology; 3. Genetic Approaches to the Biological Role of Basement Membranes: and 4. Molecular Basis of Diseases of Basement Membrane. These sessions feature a total of 12 invited speakers who have been selected on the basis of their scientific excellence and recognized ability to communicate with a broad audience. In addition, 18 short platform presentations, given primarily by young and new investigators to the field, will be selected from abstracts submitted for poster presentation. The audience, expected to consist of 200-250 participants, comprises a broad spectrum of established biochemists, structural and molecular biologists, physician-scientists and clinicians. In addition, we expect a significant number of young and new investigators in the field - students, postdoctoral fellows, and residents - to participate. We believe that the current meeting is extremely timely, and it is expected to prove its usefulness in bringing interdisciplinary approaches for the research teams of the future, as well as to enhance the translation of basic sciences to the clinical practice. In that sense, the meeting will meet some of the goals of the National Institutes of Health Roadmap Initiative.