HIV/STD Prevention for Young Adults Online

超出所提供的空间。该提案将包括：(1)为期一年的形成阶段，评估年轻人（即18至24岁之间）对网页设计的偏好，并制定最先进的基于网络的策略，促进采用预防艾滋病毒/性病的行为；(2)一项为期两年的研究，以测试在随机对照试验中招募、招收和留住青年的可行性，以研究：(a)来自聊天室和公告板的同伴支持；(b)定制的、互动的艾滋病毒/性病预防信息和应对技能对与性伴侣使用避孕套相关的知识、自我效能、结果预期和行为的影响。在前6个月，调查人员将与年轻人进行焦点小组讨论，以确定对网站设计的偏好，包括聊天室、公告板和互动组件，并生成、修改和测试可在线传递的定制风险降低信息的想法。在焦点小组调查的同时，在接下来的6个月里，调查人员将与专家网页设计师合作，将设计偏好转化为多个互联网网页。在项目的第13到31个月，我们将在互联网上实施一项随机对照试验。年龄在18岁到24岁之间、在丹佛市区诊所就诊的年轻人将被招募参加这项研究。他们将首先完成一个在线的、自我管理的安全套知识、态度和实践基线评估。然后，参与者将被随机分配到三个研究组中的一个。在第一组（对照组）中，参与者将被引导到一个带有关于艾滋病/性病预防的标准说教信息的网页。第二部分（社会支持）将引导参与者进入一个网页，他们可以在这个网页上参加在线聊天室，并在公告栏上发布有关问题的信息，包括但不限于安全套的使用。第三部分（量身定制的风险降低选项）将引导参与者进入一个网页，在那里他们将获得个性化的反馈，应对技能培训，以及。根据他们对基线评估的反应量身定制宣传安全套使用的信息，由我们称之为榜样的发言人传递。通过这一努力，我们将探索我们是否可以招募和保留足够的研究参与者样本；参与者是否遵守随机对照试验协议，按照指定的频率登录网站（包括基线、干预和随访登录）；安全套知识、自我效能和结果预期是否受到以下因素的影响：(a)在线同伴支持和/或(b)量身定制的互动信息；以及避孕套的使用是否受到：(a)在线同伴支持和/或(b)量身定制的互动信息的影响。与第一次提交的提案相比，修订后的提案有三个主要变化：它是一项可行性研究，调查预防艾滋病毒/性病的在线试验是否可能；它包含三个而不是四个研究组；这是一个为期三年而不是四年的项目。（组织，城市，州）科罗拉多州丹佛市AMC癌症研究中心科罗拉多州丹佛市卫生和医院管理局科罗拉多州丹佛市落基山脉计划生育中心（PPRM）科罗拉多州丹佛市关键人员========================================章节结束===========================================

EXCEED THE SPACE PROVIDED. This proposal will incorporate: (1) a one-year formative phase to assess youth (i.e., between 18 and 24 years old) preferences for web design and to develop state ofthe art web-based strategies promoting adoption ofHIV/STD prevention behavior; and (2) a two-year study to test the feasibility ofrecruiting, enrolling and retaining youth in a randomized, controlled trial to study the impact of: (a) peer support from chat room and bulletin boards and (b) tailored, interactive HIV/STD prevention messages and coping skills on knowledge, self-efficacy, outcome expectancies and behaviors related to condom use with sexual partners. During the first 6 months, investigators will conduct focus groups with youth to ascertain preferences for web-site design incorporating chat rooms, bulletin boards, and interactive components and to generate, modify and test ideas for tailored risk reduction messages that can be delivered online. Simultaneous to the focus groups and for 6 months thereafter, investigators will work with expert web designers, to translate design preferences to multiple Internet web pages. In months 13 through 31 ofthe project, we will implement a randomized controlled trial that will take place on the Internet. Youth between the ages of 18 and 24 who attend clinic sites in the Denver metropolitan area will be recruited to participate in the study. They will first complete an online, self-administeredbaseline assessment of condom knowledge, attitudes and practices. Participants will then be randomized to one ofthree study arms. In the first arm (control), participants will be directed to a web page with standard didactic messages about HIV/STD prevention. The second arm (social support) will direct participants to a web page on which they can take part in online chat rooms and post bulletin board messages about issues including, but not limited to, condom use. The third arm (tailored risk reduction options) will direct participants to a web page where they will receive personalized feedback, coping skills training, and.Iailored messages promoting condom use based on their responses to the baseline assessment, delivered by spokespersons we call role models. Through this effort we will explore whether we can recruit and retain an adequate sample of study participants; whether participants adhere to the randomized controlled trial protocol for logging on to web sites with assigned frequency (including baseline, intervention and follow-up log-ons); whether condom knowledge, self-efficacy,and outcome expectancies are affectedby: (a) peer support online and/or (b) tailored interactive messages; and whether condom use is affectedby: (a) peer support online and/or (b) tailored interactive messages. This revised proposal has three major changes from the first submission: it is a feasibility study, investigating whether an online trial for HIV/STD prevention is possible; it incorporates three rather than four study arms; and is a three rather than four year project. PERI~'ORNIANCESITE(S) (organization, city, state) AMC Cancer Research Center Denver, Colorado Denver Health and Hospital Authority Denver, Colorado Planned Parenthood ofthe Rocky Mountains (PPRM) Denver, Colorado KEY PERSONNEL ========================================Section End===========================================