Strengthening Bioethics Capacity and Justice in Health

描述（由申请人提供）：在稀缺和不平等的环境中进行的人类受试者研究需要对上下文敏感的道德，包括基本的跨文化价值观，并促进社会变革。我们建议通过扩大与北卡罗来纳州大学和比利时鲁汶天主教大学的伙伴关系，在刚果民主共和国金沙萨公共卫生学院（KSPH）建立生物伦理培训和研究能力。四名刚果学者将在UCL完成为期一年的生物伦理学硕士研究生强化培训课程，并在UCL完成为期5个月的生物伦理学研究开发，课程建设和IRB培训。返回刚果民主共和国后，新的KSPH生物伦理学中心（CB）的学者将加强当地IRB的能力;进行创新和社会相关的独立生物伦理学研究;开发一个为期两周的生物伦理学模块，将其纳入KSPH的MPH计划;建立生物伦理学文件和咨询服务;创建专注于发展中国家生物伦理学问题的原创教材;设计一个生物伦理学网站，发展电子学习能力，并在第四年为整个非洲法语国家的学者提供为期两周的生物伦理学强化课程。新的KSPH生物伦理学中心的各种活动将有助于其使命在刚果民主共和国和非洲法语国家促进负责任的生物医学研究和临床实践。CB将鼓励反思在贫困和不公正的情况下自主的意义;社区，研究机构和弱势受试者之间的共同责任;创造性的，文化上共鸣的解决方案，以解决生物医学研究引起的伦理冲突;承认程序知情同意的重要性和局限性，以及体现研究人员和受试者之间相互尊重的“谈判同意”的必要性。能力建设对于负责任地处理植根于地方和全球不公正的公共卫生问题至关重要，并有助于社会变革和建立新的人权文化。

DESCRIPTION (provided by applicant): Human subjects research in environments of scarcity and inequality requires context-sensitive ethics that incorporates basic transcultural values and promotes social change. We propose to build bioethical training and research capacity at the Kinshasa School of Public Health (KSPH), Democratic Republic of Congo (DRC) through expansion of its partnerships with the University of North Carolina (UNC), and the Catholic University of Louvain, Belgium (UCL). Four Congolese scholars will complete a one-year intensive postgraduate, master-level training program in Bioethics at UCL, and 5 months of mentored bioethics research development, curriculum building, and IRB training at UNC. Upon return to DRC, scholars at the new KSPH Center of Bioethics (CB), will reinforce local IRB capacity; perform innovative and socially relevant independent bioethics research; develop a two-week bioethics module integrated into the MPH program at KSPH; establish a bioethics documentation and consultation service; create original pedagogical material focusing on developing world bioethical issues; design a bioethics website and develop e-learning capacities, and in the fourth year, offer a 2-week intensive course in bioethics for scholars from throughout Francophone Africa. The diverse activities at the new KSPH Center of Bioethics will serve its mission to promote responsible biomedical research and clinical practice in DRC and in francophone Africa. The CB will encourage reflection on the meaning of autonomy in circumstances of poverty and injustice; co-responsibility between communities, research institutions and vulnerable subjects; creative, culturally resonant solutions to ethical conflicts raised by biomedical research; recognition of the importance and limits of procedural informed consent, and the need for 'negotiated consent' embodying mutual respect between researcher and subject. The CB is critical to deal responsibly with public health problems rooted in local and global injustice, and can contribute to social change and the establishment of a new human rights culture.