Online Adaptation of HIV Risk-Reduction Interventions

描述（由申请人提供）：本申请是根据PAR-03-078《从干预发展到服务》提交的：探索性研究赠款（R34），为一个为期3年的项目寻求资金，以适应和实地测试两个常用和有效的社区一级艾滋病毒预防干预措施，综合推广和民意领袖（POL）模型，用于在线环境，例如“聊天室”。“高风险个人在网上结识性伴侣变得越来越普遍。在对不同人群的多项研究中，研究人员证明，在网上寻找性伴侣的人表现出增加性风险行为的模式。互联网还具有潜在的效用，可以接触到有感染艾滋病毒风险的人群。我们认为，社区一级的干预措施（综合推广，POL），干预人口在其自然环境中的日常互动显示出特别的承诺，为适应在线使用。为了验证这一点，我们将进行三个阶段的研究：（1）与使用聊天室的人和进行在线干预的提供者进行初步访谈和焦点小组讨论（2）利用在形成阶段获得的信息，我们将根据我们对这些干预的初步概念制定治疗方案和标准化干预手册，以适应互联网，（3）我们将进行试点研究和小规模的概念测试，以检查干预措施在改变社区规范、态度和艾滋病毒危险行为方面的潜在功效。现场测试将使用随机设计，4个聊天网站随机分配到3种条件之一：（a）综合外展，（B）POL和（c）仅评估控制。与PA一致，所使用的方法将提供有关在线社区干预措施的可行性，可接受性和实用性的初步数据。所提出的方法还将允许我们收集所需的数据，以提供更大规模试验所需的初步疗效证据，包括对干预效应量等结果参数的估计。

DESCRIPTION (provided by applicant): This application, submitted in response to PAR-03-078, From Intervention Development to Services: Exploratory Research Grants (R34), seeks funding for a 3 year project to adapt and field test two commonly-used and efficacious community-level HIV prevention interventions, Integrated Outreach and the Popular Opinion Leader (POL) Model, for use in online environments such as "chat rooms." It is becoming increasingly common for high-risk individuals to meet sexual partners online. In multiple studies with diverse populations, researchers have documented that persons who seek sexual partners online show a pattern of increased sexual risk behaviors. The Internet also has potential utility to reach populations at risk for HIV. We believe that community-level interventions (Integrated Outreach, POL) which intervene with populations in their natural environment during their day-to-day interactions show particular promise for adaptation for online use. To examine this, we will conduct 3 phases of research: (1) initial interviews and focus groups with persons using chat rooms and with providers who conduct online interventions (2) using information obtained during the formative stage, we will develop treatment protocols and standardized intervention manuals building upon our preliminary conceptualization of these interventions as adapted for the Internet, (3) we will conduct pilot studies and a small-scale test-of-concept field test to examine the potential efficacy of the interventions to alter community norms, attitudes, and HIV risk behavior. The field test will use a randomized design with 4 chat sites randomly assigned to 1 of 3 conditions: (a) Integrated Outreach, (b) POL, and (c) assessment-only control. Consistent with the PA, methods used will provide preliminary data concerning the feasibility, acceptability, and practicality of online community-level interventions. The proposed methods will also permit us to collect data needed to provide initial evidence of efficacy needed for a larger-scale trial, including estimates of outcome parameters such as intervention effect sizes.