Cancer and Leukemia Group B

描述(由申请人提供)：本申请是北卡罗来纳大学教堂山分校(UNC-CH)及其附属机构提交的CALGB机构赠款的第二次竞争性续签。UNC-CH自1986年以来一直是CALGB的成员。我们的应计费用保持在大约40个治疗案例(包括6-10个少数族裔应计费用/年)加上伴随研究。我们还维护一个附属网络，负责每年另外60-90个应计项目，同时保持出色的数据质量控制。此外，我们的机构现在在乳房、癌症预防和控制、胃肠道疾病、淋巴瘤、分子病理学、放射肿瘤学等领域拥有广泛的领导参与，并是基于北卡罗来纳大学的少数民族倡议计划和基于VCU的少数民族CCOP的研究基地。此外，我们在本集团的领导努力也在继续扩大。我们现在拥有一名委员会主席、五名委员会副主席、七名委员会或工作组核心或联络成员、八名模式委员会成员、一名执行委员会成员、两名董事会成员、五名行政委员会成员和七名礼宾首席调查员。在过去的5年里，来自北卡罗来纳大学及其附属机构的成员在CALGB的各种科学、行政和领导委员会中担任了56个职位。北卡罗来纳大学-CH分校的额外教员将扩大我们在乳房、外科、GU、GI、淋巴瘤和PET委员会(F.Detterbeck、M.Graham、C.Sartor、L.Carey、J.Mohler、R.Pruthi、B.O‘Neil、R.Orlowski、P.Watkins和C.Dees)的承诺和集团领导力。因此，我们认为，这一申请反映了UNC-CH调查人员在领导力、科学和服务方面为集团提供的日益重要的贡献，以及我们通过附属成员增加应计利润的持续努力，同时保持对高质量数据提交的严格控制。我们尊重地认为，这份申请既表明了该机构对集团的当前价值，也表明了以下贡献：联合国儿童基金会及其附属机构的成员将在未来五年继续提供CALGB。

DESCRIPTION (provided by applicant): This application represents the second competitive renewal of the CALGB institutional grant submission from the University of North Carolina at Chapel Hill (UNC-CH) and its affiliates. UNC-CH has been a member of CALGB since 1986. Our accrual has been maintained at approximately 40 treatment cases (including 6-10 minority accruals/year) plus companion studies. We also maintain an affiliate network responsible for another 60-90 accruals/year while maintaining excellent data quality control. Moreover, our institution now has broad leadership participation in the Group in Breast, Cancer Prevention and Control, GI, Lymphoma, Molecular Pathology, Radiation Oncology, and is the research base for a UNC based Minority Initiative Program and a VCU based Minority CCOP. Moreover, our leadership efforts in the Group have also continued to expand. We now enjoy the distinction of having one committee chair, five committee vice-chairs, seven committee or working group core or liaison members, eight modality committee members, one Executive Committee member, two members of the Board of Directors, five administrative committee members and seven protocol principal investigators. Members from UNC and its affiliates have held 56 positions on various scientific, administrative, and leadership committees of CALGB during the past 5 years. Additional faculty at UNC-CH will expand our commitment and Group leadership in the Breast, Surgery, GU, GI, Lymphoma and PET committees (F. Detterbeck, M. Graham, C. Sartor, L. Carey, J. Mohler, R. Pruthi, B. O'Neil, R. Orlowski, P. Watkins, and C. Dees). We therefore believe that this application reflects the growing and crucial contribution that UNC-CH investigators provide to the Group in leadership, science and service as well as our continued efforts to increase accrual through affiliate members while maintaining rigorous control of quality data submission. We respectfully submit that this application demonstrates both the current value of this institution to the Group and the contributions that: the membership of UNC-CH and its affiliates will continue to provide CALGB over the next five years.