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HIGH DOSE CARBOPLATIN AND PACLITAXEL WITH G-CSF IN NON-SMALL CELL LUNG CANCER

HIGH DOSE CARBOPLATIN AND PACLITAXEL WITH G-CSF IN NON-SMALL CELL LUNG CANCER
高剂量卡铂和紫杉醇联合 G-CSF 治疗非小细胞肺癌
批准号：
6275168
负责人：
Thomas C. Shea
金额：
$1.58万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6275168
关键词：
carboplatin clinical research colony stimulating factor combination chemotherapy drug administration rate /duration human subject human therapy evaluation neoplasm /cancer chemotherapy nonsmall cell lung cancer paclitaxel

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英文摘要
The primary objective is to assess the response rate to two-21-day cycles of high dose chemotherapy with carboplatin and paclitaxel supported G-CSF and peripheral blood progenitor cells in patients with Stage III non-small cell lung cancer. The secondary objectives are: a) to evaluate the hematologic and non-hematologic toxicity of this induction treatment, and b) to evaluate the toxicity and feasibility of administering 6600 cGvXRT to nonsurgical patients who have been treated with two cycles of high-dose carboplatin and paclitaxel.
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