3D Printed Indicator Strips For Commercial Wound Dressings and Other Healthcare Products

这个项目解决了对一种廉价的一次性伤口监测方法的需求，这种方法可以很容易地整合到当前的商业伤口敷料中，为临床医生、护士和患者提供有关关键生物标志物的连续信息流。这将有助于确定伤口的状况/状态，并指出那些没有正确愈合并需要进一步医疗干预的伤口。建议的过程包括3D打印由四种不同颜色的指示剂组成的多分析物条带，这些指示剂对不同的挥发性生物标志物具有选择性。该条将提供半连续的、按需的信息流，该信息流涉及伤口上方和敷料所包含的关于不同生物标志物的顶腔的组成。这一条不会单独开发，而是与伤口敷料的国际生产商ConvaTec合作开发，后者将帮助探索3DCIS(3D色度指示条)指示器技术的能力和适用性，因为它是从一个相关的EPSRC项目中出现的，为他们现有的伤口护理产品增加价值。与一家公司的合作将解决传感器条商业化的潜在障碍，如设计和开发、监管和临床事务、供应链、制造和营销。拟议的项目与最近宣布的化学与化学工程学院的“医疗”研究主题以及昆士兰大学关于医疗材料和先进技术的PRP是一致的。拟议的项目也与EPSRC在促进医疗保健方面有影响力的研究方面的广泛努力保持一致。

This project addresses the need for an inexpensive, disposable wound monitoring method that can be readily incorporated into current commercial wound dressings providing clinicians, nurses, and patients with a continuous stream of information about key biomarkers. This will help identify the condition/status of a wound and indicate those that are not healing properly and require further medical intervention. The proposed process involves 3D printing of a multi-analyte strip comprised of four different colour-based indicators which are selective in response to different volatile biomarkers. This strip will provide a semi-continuous, on-demand, stream of information concerning the composition of the headspace above the wound and contained by the dressing with regard to the different biomarkers. This strip will not be developed in isolation, but rather with an international producer of wound dressings, ConvaTec, who will help explore the capabilities and applicability of the 3DCIS (3D colorimetric indicator strip) indicator technology as it emerges from an associated EPSRC project to add value to their existing wound-care products. Collaboration with a company will allow for potential barriers to commercialisation of the sensor strip such as design & development, regulatory and clinical affairs, supply chain, manufacturing, and marketing to be addressed. The proposed project is in line with the recently announced 'Healthcare' research theme of the School of Chemistry and Chemical Engineering and QUB's PRP on Material and Advanced Technologies for Healthcare. The proposed project is also aligned with the EPSRC's extensive efforts in promoting impactful research for healthcare.