CORE--DATABASE MANAGEMENT AND STATISTICS

马萨诸塞州ADRC建立并维护了美国最古老、最全面的AD和相关痴呆症临床数据库之一。其数据管理和统计核心的创建是为了支持该中心的使命，即对AD和相关神经退行性疾病进行创新研究，并与其他ADC和国家AD研究计划保持合作研究。其主要人员齐心协力： 维护ADRC患者登记处和神经病理学脑登记处，以满足当地ADRC和国家阿尔茨海默氏症协调中心（NACC）的需求;确保在记忆障碍单元（MDU）访问和尸检期间收集的临床，实验室和神经病理学数据无缝传输到ADRC数据库;通过计算机范围检查和双重检查程序进行准确的数据输入;根据HIPAA保证数据机密性（1996年健康保险携带和责任法案）和一般患者隐私指南;向ADRC和（国际）国内授权的研究者提供所需数据，以支持他们的研究工作;向NACC提交及时准确的临床和神经病理学数据;在各种核心和附属研究项目中为ADRC研究人员提供高质量的统计咨询和执行。

The Massachusetts ADRC established and maintains one of the oldest and most comprehensive clinical databases on AD and related dementias in the country. Its Data Management and Statistics Core was created to support the Center's mission of conducting innovative research on AD and related neurodegenerative disorders, and to sustain collaborative research efforts with other ADCs and national AD research initiatives. Its key personnel work cohesively to: Maintain the ADRC Patient Registry and Neuropathology Brain Registry to serve local ADRC and National Alzheimer's Coordinating Center (NACC) needs; Ensure a seamless transmission of clinical, laboratory and neuropathology data collected during Memory Disorders Unit (MDU) visits and autopsies to the ADRC database; Conduct accurate data entry monitored by computerized range checks and double-checking procedures; Guarantee data confidentiality in accordance with HIPAA (Health Insurance Portability and Accountability Act of 1996) and general patient privacy guidelines; Provide requested data to authorized investigators, both within the ADRC and (inter)nationally, in support of their research endeavors; Submit timely and accurate clinical and neuropathology data to the NACC; Deliver top-quality statistical consultation and execution to ADRC investigators in the various cores and affiliated research projects.