Expression and functions of leukocyte Immunoglobulin-like Receptor (LIR)-6 and LIR-4 in inflammatory arthritis (IA).

类风湿关节炎（RA）影响着全世界数百万人，其特点是免疫细胞不受控制的激活破坏了自己的关节。这种细胞过度激活的原因尚不清楚，现有的治疗仅限于缓解症状。我们将研究名为白细胞igg样受体的新蛋白在调节免疫细胞激活中的作用。了解控制免疫细胞不必要激活的机制对于预防和治疗类风湿性关节炎至关重要。

Rheumatoid arthritis (RA) that affects millions worldwide is characterised by uncontrolled activation of immune cells destroying ones own joints. The reasons for this excessive activation of cells are not known and existing treatments are limited to easing symptoms. We will study the role of new proteins named as Leucocyte Ig-like Receptors in regulating immune cell activation. Understanding mechanisms that control unwanted activation of immune cells is critical in preventing and treating RA.