Gene Ontology Consortium

产品说明：（申请人提供）基因本体（GO）联盟是模式生物数据库组、基因组注释中心和其他积极从事基因组、基因和基因产物注释的组织之间的合作。通过共同制定和采用语义标准，为共同数据库做出贡献，并向科学界免费传播我们的资源，我们促进和提高科学家利用所有可用信息的能力，以进一步了解人类健康和疾病。 GO Consortium的目标是：1）构建和支持分子功能、生物过程、细胞组分和序列特征的本体; 2）支持模式生物数据库、基因组注释中心等对这些本体的基因组、基因和基因产物的注释; 3）提供对本体的广泛开放和公共访问，基因产品注释和支持工具和文档通过一个共同的数据资源和4）扩大我们的社区通过主办用户会议，为GO联盟增加新的数据库组，并探索创新研究，推动GO联盟致力于找到语义集成问题的实际解决方案。 此更新申请旨在支持GO的持续开发和使用。该项目在此期间的主要扩展包括在正式本体语言中实施GO，实现序列特征的本体，以及将GO作为统一医学语言系统（UMLS）的一个组成部分。

DESCRIPTION: (provided by applicant) The Gene Ontology (GO) Consortium is a collaboration among model organism database groups, genome annotation centers and others who are actively engaged in the annotation of genomes, genes and gene products. By sharing in the development and adoption of semantic standards, by contributing to a common data repository, and by disseminating our resources freely to the scientific community, we promote and enhance the ability of scientists to use all available information to further the understanding of human health and disease. The objectives of the GO Consortium are 1) to build and support ontologies for molecular function, biological process, cellular component and sequence features; 2) to support the annotation of genomes, genes and gene products to these ontologies by model organism databases, genome annotation centers and others; 3) to provide extensive open and public access to the ontologies, the gene product annotations and supporting tools and documentation via a common data resource and 4) extend our community through hosting Users Meetings, adding new database groups to the GO Consortium, and exploring innovative research that advances the GO Consortium's commitment to finding practical solutions to semantic integration issues. This renewal application proposes to support the continued development and use of the GO. Major extensions of the project in this granting period include the implementation of the GO in formal ontological language, the realization of an ontology for sequence features, and the inclusion of the GO as a component of the Unified Medical Language System (UMLS).