The effects of personality, motivation and self-efficacy on very low-calorie diet in type 2 Diabetes

糖尿病是世界范围内的一个重大公共卫生问题。在英国，与糖尿病相关的医疗支出估计每年花费NHS GB 100亿英镑。通过非常低卡路里的饮食(每天800卡路里)减肥，在治疗2型糖尿病方面取得了很好的效果。然而，治疗并不总是成功的，许多患者发现很难维持下去。这其中的原因尚不清楚，但研究表明，个性和动机可能是理解为什么一些患者可以维持饮食，而另一些患者则不能。这个博士项目将集中评估在2型糖尿病护理中采用极低热量饮食时个性特征和动机的影响。该项目将从南方健康国民健康保险制度基金会信托糖尿病服务机构招募被诊断为2型糖尿病的参与者。作为他们护理的一部分，他们将开始非常低卡路里的饮食，并将接受为期一年的跟踪调查。关键结果将是体重和血糖水平的变化，调查个性和动机对坚持的影响。总体而言，该项目将采用混合方法设计来评估个性和动机对坚持极低卡路里饮食的影响。这将是一项纵向队列研究，定性地探索参与者对低卡路里饮食的体验和成功的障碍。研究结果将被用于开发进一步的干预性试验，旨在个性化节食和支持2型糖尿病患者。

Diabetes is a major public health issue worldwide. In the UK, the health expenditure associated withdiabetes is estimated to cost the NHS £10 billion per year. Weight loss through a very low-calorie diet(800 calories a day) has shown great results in the management of type 2 diabetes. However, thetreatment is not always successful, with many patients finding it difficult to maintain. The reasons for thisare unclear, but research suggests that personality and motivation may be key factors to understandingwhy some patients can sustain the diet and others not.This PhD project will focus on assessing the impact of personality traits and motivation when adopting avery low-calorie diet in type 2 diabetes care. The project will recruit participants from Southern HealthNHS foundation trust diabetes service who have been diagnosed with type 2 diabetes. As part of theircare they will be starting a very low-calorie diet and will be followed up for a 1-year period. The keyoutcome measures will be changes in body weight and glucose levels, investigating the impact ofpersonality and motivation on adherence.Overall this project will employ a mixed-methods design to assess the impact of personality andmotivation on adherence to very low-calorie diets. This will be a longitudinal cohort study that alsoexplores qualitatively participants' experience of a low-calorie diet and barriers to success. The resultswill be used to develop further interventional trials which will aim to personalise dieting and support tothose with type 2 diabetes.