Cognitive-Behavioral Therapy for Pathological Gambling

描述（由候选人提供）：病理性赌博是一种相对常见的疾病，其特征是赌博行为的持续性和复发性适应不良模式。病理性赌博与严重的个人痛苦和高比率的功能障碍和犯罪行为有关。尽管它的公共卫生意义，它收到了很少的实证研究。 在这份申请中，我提出了一项有组织的培训计划，并监督了针对病理性赌博的研究。虽然有这种疾病的现象学和心理学治疗的背景，我需要在以下领域的额外培训：1）循证心理治疗，特别是认知行为治疗和动机访谈; 2）干预研究设计和方法;和3）生物统计学和负责任的研究行为。将培训以文件形式进行 与一个研究项目相结合，我建议将认知行为疗法和动机访谈用于治疗病态赌博，并在一项对照研究中对这种心理社会干预进行初步测试，该研究涉及68名随机接受这种干预或转介到赌徒匿名会的受试者。该项目的研究结果将导致R-01在K-23奖的第4年应用，将认知行为疗法与动机访谈与病理性赌博的药物疗法进行比较。 该奖项将为我进一步研究病理性赌博的治疗以及独立的以患者为导向的研究生涯的培训提供必要的背景。

DESCRIPTION (provided by candidate): Pathological gambling is a relatively common disorder characterized by persistent and recurrent maladaptive patterns of gambling behavior. Pathological gambling is associated with significant personal distress and high rates of both functional impairment and criminal behavior. Despite its public health significance, it has received little empirical investigation. In this application for a Mentored Patient-Oriented Research Career Development Award (K-23), I have proposed an organized program of training and supervised research focusing on pathological gambling. While have a background in the phenomenology and psychopharmaoclogical treatment of this disorder, I require additional training in the following areas: 1) evidence-based psychotherapy, specifically cognitive-behavioral therapy and motivational interviewing; 2) intervention study design and methodology; and 3) biostatistics and the responsible conduct of research. This training will be integrated with a research project in which I propose to adapt cognitive-behavioral therapy and motivational interviewing to the treatment of pathological gambling and pilot test this psychosocial intervention in a controlled study involving sixty-eight subjects randomized to this intervention or referral to Gamblers Anonymous. Findings from this project will lead to an R-01 application during year 4 of the K-23 Award comparing cognitive-behavioral therapy with motivational interviewing to pharmacotherapy in pathological gambling. This award would provide me with the necessary background for further studies in the treatment of pathological gambling and the training for an independent patient-oriented research career.