Texas A&M University Interdisciplinary Life Sciences Building Build-Out

德克萨斯A&M大学要求约350万美元在其新的跨学科生命科学大楼（ILSB）的二楼建造12，680平方英尺的可分配外壳空间。该项目的资金将用于完成四个最先进的研究实验室，以及共享设备室和冷藏室空间。这个空间是为四个研究人员在结构生物学，合成化学药物发现，分子病毒学和癌症生物学。这些实验室靠近核心支持实验室，这对其研究的成功至关重要。ILSB的建设将于2009年夏季完成，并定于2009年秋季开始占领。然而，ILSB的计划是，在未来七年内，随着资金的确定，将建造约40%的实验室空间。拟议的翻新占剩余外壳空间的55%，将使德克萨斯A&M加快ILSB建设完成的步伐。 ILSB的使命是将多个生命科学学科整合在一个地点，以促进合作寻找复杂问题的解决方案。为此，ILSB的科学家将把他们的研究集中在三个相互关联的主要领域：结构生物学，神经科学和癌症研究。从基础研究到新药发现的快速转化是贯穿癌症、神经疾病和许多其他疾病研究的共同主线，而利用高通量药物筛选和分子结构测定等技术的力量可以促进这一过程。德克萨斯A&M在其长期计划“2020年愿景”中包括促进，管理和资助跨学科奖学金，研究和教学的目标。生命科学被确定为两个高度优先的举措之一，建设一个多用途的生命科学中心被确认为实现大学愿景的首要任务。该建筑计划包括自然采光的开放区域，这将促进和刺激研究人员之间的自发和正式互动，旨在促进尖端的跨学科研究合作。ILSB还将容纳大学核心实验室，如质谱，蛋白质晶体学，光学和电子显微镜成像中心，以及一个动物园，以及信息学基础设施，会议，研讨会和演讲室，加上一个295个座位的礼堂。这座最先进的设施采用绿色和可持续原则设计，并按照LEED“银”认证标准建造。此外，实验室采用模块化结构设计，以便在不同的研究项目分配到大楼时进行重新配置，以获得设施的最佳利用。ILSB位于校园中间，将成为一个研究中心，加强整个德克萨斯A&M大学生命科学研究人员之间的协作互动。

DESCRIPTION (provided by applicant): Texas A&M University requests ~$3.5 million to build out 12,680 sq ft of assignable shell space on the second floor of its new Interdisciplinary Life Sciences Building (ILSB). Funding of this Specific Aim will complete four state-of-the-art research laboratories plus shared equipment rooms and cold room space. This space is intended for four researchers in structural biology, synthetic chemistry-drug discovery, molecular virology, and cancer biology. The laboratories are in close proximity to core support laboratories, critical for the success of their research. Construction of the ILSB will be finished in Summer 2009 and occupation is slated to begin in Fall 2009. The ILSB was planned, however, so that ~40% of laboratory space would be built out over the next seven years as funds are identified. The proposed renovation represents ~55% of the remaining shell space and will enable Texas A&M to accelerate the pace at which the build-out of the ILSB is completed. The mission of the ILSB is to integrate multiple life science disciplines in one location in order to promote the collaborative search for solutions to complex problems. To this end, scientists in the ILSB will focus their research in three interconnected major areas: structural biology, neurosciences, and cancer research. Rapid translation of basic research to novel drug discovery is the common thread running through research on cancer, neural disorders, and many other diseases, and it is facilitated by harnessing the power of techniques like high-throughput drug screening and molecular structure determination. Texas A&M included in its long-term plan, Vision 2020, the goal of promoting, administering, and funding interdisciplinary scholarship, research, and teaching. Life sciences was identified as one of two high-priority initiatives, and construction of a multi-use Life Sciences Center was affirmed as paramount to achieving the University's vision. The building was planned to include naturally-lighted, open areas that will facilitate and stimulate spontaneous and formal interactions among researchers, with the goal of promoting cutting-edge interdisciplinary research collaborations. The ILSB also will house university core laboratories, such as mass spectrometry, protein crystallography, a light and electron microscopy imaging center, and a vivarium, as well as informatics infrastructure, meeting, seminar, and lecture rooms, plus a 295-seat auditorium. This state-of-the-art facility was designed using green and sustainable principles and was constructed to meet LEED "Silver" Certification standards. Furthermore, the laboratories were designed with a modular structure so that they could be reconfigured as different research programs are assigned to the building in order to obtain the best use of the facility. Situated in the middle of campus, the ILSB will become a research hub enhancing collaborative interactions among life science researchers throughout Texas A&M University.