FASEB Conference: Glucose Transporter Biology

描述(由申请人提供)： 这是一份申请申请，请求部分支持由美国实验生物学学会联合会(FASE B)主办的夏季研究会议“葡萄糖转运蛋白生物学”。本次会议定于2005年8月5日至8月11日在科罗拉多州斯诺马斯村举行。这将是第七届致力于葡萄糖运输和代谢的细胞、分子和生理调节的双年度国际会议。本次会议的目的是关注对我们的理解有直接影响的新颖、尖端的方法和发现，1)维持正常血糖稳态所必需的复杂调控过程，2)导致这一过程调节失调导致胰岛素抵抗和糖尿病的病理条件。这次会议提供了一个场所，鼓励和促进新的年轻研究人员在这一关键的疾病研究领域。本次会议将限于150名与会者，他们来自具有临床和/或基础科学背景的个人，根据他们的专业知识和兴趣进行挑选。将有八个主要的科学会议，包括4-6次受邀演讲(25分钟+5分钟讨论)，然后15-30分钟的时间将提出选定的摘要和/或“最新数据”。在每届会议结束时，将有时间进行一般性讨论。海报还将在整个会议期间张贴。选定海报摘要的口头介绍和海报会议本身将为初级参与者提供与该领域专家直接互动和讨论其数据的机会。会议的主题是：1)囊泡运输的信号调节，2)葡萄糖传感和营养利用，3)信号和葡萄糖代谢的新见解，4)病理生理学和葡萄糖运输调节，5)GLUT4运输：多水平调节，6)谷氨酸和其他代谢调节因子的转录调节，7)研究过剩功能的新方法，以及8)燃料代谢调节。将界定和讨论每一届会议中存在的共识、争议和不确定性领域。与以往一样，本次会议的互动环境将促进与会者之间的合作努力，并将确定未来的关键目标，以帮助我们理解葡萄糖转运蛋白的调节和负责维持葡萄糖稳态的机制。

DESCRIPTION (provided by applicant): This is an application requesting partial support for a summer research conference entitled "Glucose Transporter Biology" sponsored by the Federation of American Societies for Experimental Biology (FASEB). This conference is scheduled for August 5 to August 11, 2005 in Snowmass Village, CO. This will be the 7th bi-annual international meeting devoted to the cellular, molecular and physiological regulation of glucose transport and metabolism. The aim of this conference is to focus on novel, cutting-edge approaches and findings that have a direct impact on our understanding of 1) the complex regulatory processes that are necessary to maintain normal glucose homeostasis, and 2) the pathological conditions that result in dysregulation of this process resulting in insulin resistance and diabetes. This conference provides a venue to encourage and promote new young investigators in this critical area of disease research. This conference will be limited to 150 participants from individuals with clinical and/or basic science backgrounds, selected on the basis of their expertise and interests. There will be eight major scientific sessions consisting of 4-6 invited talks (25 min + 5 min discussion) followed by a 15-30 min period where selected abstracts and/or "late breaking data" will be presented. At the end of each session there will be time for a general discussion. Posters will also be displayed throughout the duration of the meeting. The oral presentation of selected poster abstracts and the poster sessions themselves will provide opportunities for junior participants to directly interact with and discuss their data with experts in the field. The session topics are: 1) Signal regulation of vesicle trafficking, 2) Glucose sensing and nutrient utilization, 3) New insights into signaling and glucose metabolism, 4) Pathophysiology and glucose transport regulation, 5) GLUT4 trafficking: regulation at multiple levels, 6) Transcriptional regulation of GLUTs and other modulators of metabolism, 7) Novel approaches to study GLUT functions, and 8) Regulation of fuel metabolism. The areas of agreement, controversy, and uncertainty within each of these sessions will be defined and discussed. As has previously been the case, the interactive environment at this conference will stimulate collaborative efforts among the conferees and will identify the future critical goals for our understanding of glucose transporter regulation and the mechanisms responsible for the maintenance of glucose homeostasis.