Conference Proposal: The Biology and Chemistry of Vision

描述（由申请人提供）：这是一个关于“视觉的生物学和化学”会议的部分资金的申请，在FASEB的主持下举行，将于2005年6月18日至23日在亚利桑那州图森市的Omni度假村举行。本次会议延续了其对视觉科学基础和临床相关研究知识的贡献的卓越传统。它是自1985年以来在不同地点举行的前十次FASEB会议的成功系列的一部分。这次会议对于传播这一重要领域的最新研究成果以及吸引众多年轻和成熟的科学家参与视觉科学非常宝贵，从而为这一研究领域的新思想做出了巨大贡献。生物化学，分子生物学，生理学，生物物理学和遗传学的多学科方法有助于该计划的有效性。本次会议的目的是主要集中在感光细胞组件参与发展，视觉转导，暗适应和细胞维护。特别强调的是，有助于我们了解基因突变如何导致视力丧失，如视网膜色素变性和年龄相关性黄斑变性发生的机制的理解。拟议的会议将包括光感受器的生物学和生理学，人类遗传学和视网膜疾病，以及隐性和显性营养不良的基因治疗的主题。

DESCRIPTION (provided by applicant): This is an application for partial funding of the conference on "The Biology and Chemistry of Vision", held under the auspices of FASEB, which will take place at the Omni Resort, Tucson, AZ on June 18-23, 2005. This conference continues the ongoing tradition of excellence in its contribution to knowledge of basic and clinically relevant research in vision science. It is part of a successful series of ten previous FASEB conferences held at various locations since 1985. This conference has been invaluable for disseminating the newest research results in this important field, as well as for having attracted numerous young and established scientists to visual science, thereby greatly contributing to new ideas in this field of research. Multidisciplinary approaches in biochemistry, molecular biology, physiology, biophysics, and genetics have contributed to the efficacy of this program. This conference is designed to focus primarily on photoreceptor cell components involved in development, visual transduction, dark adaptation, and cell maintenance. Particular emphasis is given to the understanding of mechanisms contributing to our knowledge of how genetic mutations can lead to visual loss such as occurs in retinitis pigmentosa and age-related macular degeneration. Proposed sessions will include topics on the biology and physiology of photoreceptors, human genetics and retinal disease, as well as gene therapy of recessive and dominant dystrophies.