Eugene P. Cronkite Symposium

描述（由申请人提供）：本提案要求为将于2006年5月24日至26日在纽约长岛厄普顿布鲁克海文国家实验室举行的为期2天半的会议提供部分资金。 尤金P.克朗凯特研讨会以实验血液学和放射生物学先驱的荣誉命名。 会议预计将吸引150名与会者，包括来自美国各地的科学家和临床医生，包括纽约、康涅狄格州和新泽西三州地区。 预计世界各地接受克朗凯特博士培训的大约25名科学家也将出席会议。 会议的目标是（i）促进造血、辐射生物学和辐射反应规划和治疗领域的科学家和专家之间的互动，（ii）为有前途的年轻研究人员提供展示他们的研究工作并与该领域领导人互动的机会。内容包括：（1）细胞周期的调控和造血细胞的分化;（2）细胞因子疗法在恶性血液病治疗中的应用;（3）急性和慢性白血病的机制和治疗;（4）辐射对细胞周期、白血病转化、DNA修复、基因表达和细胞间信号传导的影响;（5）治疗辐射诱发造血综合征的当前和新方法，以及（6）用于管理个人暴露于放射性物质导致的小体积和大规模伤亡情况的卫生保健响应规划。

DESCRIPTION (provided by applicant): This proposal requests partial funding for a 2-1/2 day conference that will be held on May 24-26 2006 at the Brookhaven National Laboratory, Upton, Long Island, New York. The Eugene P. Cronkite Symposium is named in honor of a pioneer in experimental hematology and radiation biology. The conference is anticipated to attract 150 participants, including scientists and clinicians from throughout the USA, including the tri-state area of New York, Connecticut and New Jersey. It is also anticipated that approximately 25 scientists trained by Dr. Cronkite from around the world will attend the conference. The goals of the conference are to (i) promote interactions amoung scientists and experts in the fields of hematopoeisis, radiation biology and radiation response planning and treatment, and (ii) provide the opportunity for promising young investigators to present their research work and interact with leaders in the field. Topics to be covered include (1) regulation of cell cycle and differentiation of hematopoietic cells, (2) application of cytokine therapy to treatment of hematologic malignancies, (3) mechanisms and treatment of acute and chronic leukemias, (4) effects of radiation on the cell cycle, leukemic transformation, DNA repair, gene expression and intercellular signaling, (5) current and new approaches to treatment of radiationinduced hematopoietic syndrome, and (6) healthcare response planning for management of small volume and mass casualty scenarios resulting from exposure of individuals to radioactive material.