Heart failure Exercise And Resistance Training CAMP

描述（由申请方提供）：鉴于约500万美国HF患者出现运动不耐受、疲劳和呼吸困难的衰弱症状以及身体不适，因此在心力衰竭（HF）患者中启动和维持规律运动行为的替代模型至关重要（American Heart Association，2004）。很少有HF患者进行美国心脏协会推荐的定期锻炼（Pina等人，2003年），并且在没有正式康复计划的补偿的情况下，开始锻炼是困难的。因此，本研究的目的是测试一种创新的运动训练营干预的可行性，称为心脏训练营（心力衰竭运动和阻力训练营）。HEART CAMP源自社会认知理论（Bandura，1997），旨在教导HF患者如何锻炼和自我管理运动行为。具体目标是：（1）初步测试心脏营地干预与注意力控制随时间推移对HF患者的影响（3周、3个月和6个月）：估计能量消耗、运动自我效能和坚持运动的主要结局;症状、生物标志物、身心功能和生活质量的次要结局;（2）估计结果中组间差异的效应量，以确定更大规模调查的样本量;（3）评估HEART CAMP研究在更大规模调查中的可行性，包括：干预中使用的方法和策略;数据收集方法;和结果测量的可靠性估计。将采用实验性重复测量设计，将受试者随机分配至HEART CAMP干预组或注意力控制组，并在基线、3周、3个月和6个月进行结局测量。运动训练研究有HF，但是运动训练研究的损耗率和长期运动行为的维持仍然是个问题。HEART CAMP干预是解决慢性病HF患者这些问题的一种急需的方法。

DESCRIPTION (provided by the applicant): Alternative models for initiating and maintaining regular exercise behavior in heart failure (HF) patients are essential given the debilitating symptoms of exercise intolerance, fatigue and dyspnea and the physical deconditioning experienced by the approximately 5.0 million Americans with HF (American Heart Association, 2004). Few HF patients engage in regular exercise as recommended by the American Heart Association (Pina et al., 2003) and initiation of exercise is difficult without reimbursement for formal rehabilitation programs. Therefore, the goal of this study is to test the feasibility of an innovative exercise training camp intervention called HEART CAMP (Heart failure Exercise And Resistance Training CAMP). HEART CAMP is derived from social cognitive theory (Bandura, 1997) and purposes to teach HF patients how to exercise and self-manage exercise behavior over time. Specific aims are: (1) To pilot test the impact of the HEART CAMP intervention versus attention control in HF patients over time (3 weeks, 3 and 6 months) on: primary outcomes of estimated energy expenditure, self-efficacy to exercise, and adherence to exercise; and secondary outcomes of symptoms, biomarker, physical and psychological functioning and quality of life; (2) To estimate effect sizes for group differences in outcomes to determine sample size for a larger investigation; (3) To evaluate the feasibility of the HEART CAMP study for a larger investigation including: methods and strategies used in the intervention; data collection methods; and reliability estimates of outcome measures. An experimental repeated measures design with randomization of subjects to either the HEART CAMP intervention group or the attention control group will be used with outcome measures at baseline, 3 weeks, 3 and 6 months. Exercise training studies have HF, however attrition rates from exercise training studies and maintenance of long-term exercise behavior remains problematic. The HEART CAMP intervention is a much-needed approach to address these issues in chronically ill HF patients.