Carolina Mammography Registry

描述（由申请人提供）：本提案是为了响应国家癌症研究所的RFA CA-05-502，以支持作为乳腺癌监测联盟（BCSC）的一部分，已经成为卡罗来纳州乳房x线摄影登记处（CMR）的基础设施的继续建设和维护。BCSC是一个由七个乳房x线摄影注册中心组成的协作网络，与病理和肿瘤注册中心有联系。我们建议在北卡罗来纳州的一个地区继续开展CMR的工作。前瞻性基于实践的数据将直接从乳房x光检查机构的妇女和专业人员那里收集，包括：人口统计数据、乳房病史数据、家族史、激素使用、乳房x光检查的原因和结果、解决筛查评估所需的其他影像学研究数据以及随访建议。病理数据将前瞻性地从几个来源收集，包括直接从乳房x光检查设施、从快速病例报告系统和从NC中央癌症登记处收集的所有乳腺癌记录的年度完整电子下载。随着知情同意的加入，以及进行特殊调查的能力，CMR将能够提供数据，以提高研究乳腺癌筛查、诊断、治疗和生存的能力。CMR中的数据代表了北卡罗莱纳州人口的多样性和乳房x光检查设施的多样性。所有数据将与BCSC统计协调中心（BCSC）共享，由BCSC和外部调查人员组成的登记处的调查人员进行汇总分析。将努力提高CMR和BCSC在北卡罗来纳州的知名度，以加强对研究、规划和教育数据的利用。

DESCRIPTION (provided by applicant): This proposal is in response to RFA CA-05-502 from the National cancer Institute, to support continued building and maintenance of the infrastructure that has become the Carolina Mammography Registry (CMR), as part of the Breast Cancer Surveillance Consortium (BCSC). The BCSC is a collaborative network of seven mammography registries with linkages to pathology and tumor registries. We propose to continue the work of CMR for a region of North Carolina. Prospective practice-based data will be collected directly from women and professionals in mammography facilities including: demographic data, breast history data, family history, hormone use, reason for and findings on the screening mammogram, data on other imaging studies necessary to resolve the screening assessment, and recommendations for follow-up. The pathology data will be collected prospectively from several sources including directly from mammography facilities, from a rapid case reporting system and annual complete electronic download of all breast cancer records from the NC Central Cancer Registry. With the addition of informed consent, and the ability to do special surveys, CMR will be able to contribute data to enhance the ability to study screening, diagnosis, treatment and survival for breast cancer. The data in CMR represents the diversity of the population of North Carolina and the diversity of the mammography facilities. All data will be shared with the Statistical Coordinating Center of the (BCSC) for pooled analyses by the investigators of the Registries comprising BCSC and outside investigators. Efforts will be made to increase the visibility of both CMR and the BCSC in North Carolina, to enhance use of the data for research, planning and education.